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Page 1
Covalent Plant Natural Product that Potentiates Antitumor Immunity.
Takemoto M, Delghandi S, Abo M, Yurimoto K, Odagi M, Singh VP, Wang J, Nakagawa R, Sato SI, Takemoto Y, Farrag AMAS, Kawaguchi Y, Nagasawa K, Honjo T, Chamoto K, Uesugi M. Takemoto M, et al. Among authors: honjo t. J Am Chem Soc. 2025 Jan 10. doi: 10.1021/jacs.4c17837. Online ahead of print. J Am Chem Soc. 2025. PMID: 39794153
Impaired development of memory B cells and antibody responses in humans and mice deficient in PD-1 signaling.
Ogishi M, Kitaoka K, Good-Jacobson KL, Rinchai D, Zhang B, Wang J, Gies V, Rao G, Nguyen T, Avery DT, Khan T, Smithmyer ME, Mackie J, Yang R, Arias AA, Asano T, Ponsin K, Chaldebas M, Zhang P, Peel JN, Bohlen J, Lévy R, Pelham SJ, Lei WT, Han JE, Fagniez I, Chrabieh M, Laine C, Langlais D, Gruber C, Al Ali F, Rahman M, Aytekin C, Benson B, Dufort MJ, Domingo-Vila C, Moriya K, Shlomchik M, Uzel G, Gray PE, Suan D, Preece K, Chua I, Okada S, Chikuma S, Kiyonari H, Tree TI, Bogunovic D, Gros P, Marr N, Speake C, Oram RA, Béziat V, Bustamante J, Abel L, Boisson B, Korganow AS, Ma CS, Johnson MB, Chamoto K, Boisson-Dupuis S, Honjo T, Casanova JL, Tangye SG. Ogishi M, et al. Among authors: honjo t. Immunity. 2024 Dec 10;57(12):2790-2807.e15. doi: 10.1016/j.immuni.2024.10.014. Epub 2024 Nov 26. Immunity. 2024. PMID: 39603236
Enhanced design of pCMViR-TSC plasmid vector for sustainably high cargo gene expression in mammalian cells.
Sakaguchi M, Kinoshita R, Tomonobu N, Sakaguchi Y, Futami J, Yamauchi A, Murata H, Yamamoto KI, Takahashi T, Gohara Y, Ochi T, Jiang F, Komalasari NLGY, Chen Y, Ruma IMW, Sumardika IW, Zhou J, Honjo T, Kuribayashi F, Sagayama K, Toyooka S, Kondo E, Inoue Y. Sakaguchi M, et al. Among authors: honjo t. In Vitro Cell Dev Biol Anim. 2024 Dec;60(10):1215-1227. doi: 10.1007/s11626-024-00992-2. Epub 2024 Nov 21. In Vitro Cell Dev Biol Anim. 2024. PMID: 39570532 Free PMC article.
Discovery of a potent orally available pyrazolopyridone derivative as a novel selective bromodomain and extra-terminal domain (BET)-first bromodomain (BD1) inhibitor.
Hagihara S, Ishizawa K, Soga K, Honjo T, Takai S, Kawano Y, Kikuchi M, Nishidate A, Matsumoto F, Murase M, Hashimoto N, Sasaki C, Miyaguchi I, Okada O, Akashi T, Nakayama S, Ogasawara Y, Endo J. Hagihara S, et al. Among authors: honjo t. Bioorg Med Chem Lett. 2024 Sep 1;109:129849. doi: 10.1016/j.bmcl.2024.129849. Epub 2024 Jun 12. Bioorg Med Chem Lett. 2024. PMID: 38876177
Dissection of the signal transduction machinery responsible for the lysyl oxidase-like 4-mediated increase in invasive motility in triple-negative breast cancer cells: mechanistic insight into the integrin-β1-NF-κB-MMP9 axis.
Jiang F, Chen Y, Tomonobu N, Kinoshita R, Komalasari NLGY, Kasano-Camones CI, Ninomiya K, Murata H, Yamamoto KI, Gohara Y, Ochi T, Ruma IMW, Sumardika IW, Zhou J, Honjo T, Sakaguchi Y, Yamauchi A, Kuribayashi F, Futami J, Kondo E, Inoue Y, Toyooka S, Sakaguchi M. Jiang F, et al. Among authors: honjo t. Front Oncol. 2024 May 28;14:1371307. doi: 10.3389/fonc.2024.1371307. eCollection 2024. Front Oncol. 2024. PMID: 38863623 Free PMC article.
Lysyl oxidase-like 4 promotes the invasiveness of triple-negative breast cancer cells by orchestrating the invasive machinery formed by annexin A2 and S100A11 on the cell surface.
Takahashi T, Tomonobu N, Kinoshita R, Yamamoto KI, Murata H, Komalasari NLGY, Chen Y, Jiang F, Gohara Y, Ochi T, Ruma IMW, Sumardika IW, Zhou J, Honjo T, Sakaguchi Y, Yamauchi A, Kuribayashi F, Kondo E, Inoue Y, Futami J, Toyooka S, Zamami Y, Sakaguchi M. Takahashi T, et al. Among authors: honjo t. Front Oncol. 2024 Mar 26;14:1371342. doi: 10.3389/fonc.2024.1371342. eCollection 2024. Front Oncol. 2024. PMID: 38595825 Free PMC article.
835 results