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GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth.
Mohamedali KA, Aguirre B, Lu CH, Chandla A, Kejriwal N, Liu L, Chan AM, Cheung LH, Kok S, Duarte S, Alvarez de Cienfuegos A, Casero D, Rosenblum MG, Wadehra M. Mohamedali KA, et al. Among authors: chan am. J Immunother Cancer. 2024 Dec 22;12(12):e008891. doi: 10.1136/jitc-2024-008891. J Immunother Cancer. 2024. PMID: 39794935 Free PMC article.
EMP2 Is a Novel Regulator of Stemness in Breast Cancer Cells.
Dillard C, Kiyohara M, Mah V, McDermott SP, Bazzoun D, Tsui J, Chan AM, Haddad G, Pellegrini M, Chang YL, Elshimali Y, Wu Y, Vadgama JV, Kim SR, Goodglick L, Law SM, Patel DD, Dhawan P, O'Brien NA, Gordon LK, Braun J, Lazar G, Wicha MS, Wadehra M. Dillard C, et al. Among authors: chan am. Mol Cancer Ther. 2020 Aug;19(8):1682-1695. doi: 10.1158/1535-7163.MCT-19-0850. Epub 2020 May 25. Mol Cancer Ther. 2020. PMID: 32451329 Free PMC article.
89Zr-ImmunoPET for the Specific Detection of EMP2-Positive Tumors.
Chan AM, Olafsen T, Tsui J, Salazar FB, Aguirre B, Zettlitz KA, Condro M, Wu AM, Braun J, Gordon LK, Ashki N, Whitelegge J, Xu S, Ikotun O, Lee JT, Wadehra M. Chan AM, et al. Mol Cancer Ther. 2024 Jun 4;23(6):890-903. doi: 10.1158/1535-7163.MCT-23-0465. Mol Cancer Ther. 2024. PMID: 38417138
EMP2 Serves as a Functional Biomarker for Chemotherapy-Resistant Triple-Negative Breast Cancer.
Chan AM, Aguirre B, Liu L, Mah V, Balko JM, Tsui J, Wadehra NP, Moatamed NA, Khoshchehreh M, Dillard CM, Kiyohara M, Elshimali Y, Chang HR, Marquez-Garban D, Hamilton N, Pietras RJ, Gordon LK, Wadehra M. Chan AM, et al. Cancers (Basel). 2024 Apr 12;16(8):1481. doi: 10.3390/cancers16081481. Cancers (Basel). 2024. PMID: 38672563 Free PMC article.
Blockade of epithelial membrane protein 2 (EMP2) abrogates infection of Chlamydia muridarum murine genital infection model.
Shimazaki K, Chan AM, Moniz RJ, Wadehra M, Nagy A, Coulam CP, Mareninov S, Lepin EM, Wu AM, Kelly KA, Braun J, Gordon LK. Shimazaki K, et al. Among authors: chan am. FEMS Immunol Med Microbiol. 2009 Mar;55(2):240-9. doi: 10.1111/j.1574-695X.2008.00525.x. Epub 2009 Jan 12. FEMS Immunol Med Microbiol. 2009. PMID: 19159428 Free PMC article.
205 results