Mace EM - Search Results

1

The Golgi complex governs natural killer cell lytic granule positioning to promote directionality in cytotoxicity.

Pedroza LA, van den Haak F, Frumovitz A, Hernandez E, Hegewisch-Solloa E, Orange TK, Sheehan KB, Prockop S, Bodansky A, Chinn IK, Lupski JR, Posey JE, Mace EM, Li Y, Orange JS. Pedroza LA, et al. Among authors: mace em. Cell Rep. 2025 Jan 13;44(1):115156. doi: 10.1016/j.celrep.2024.115156. Online ahead of print. Cell Rep. 2025. PMID: 39813120 Free article.

2

Lytic immune synapse function requires filamentous actin deconstruction by Coronin 1A.

Mace EM, Orange JS. Mace EM, et al. Proc Natl Acad Sci U S A. 2014 May 6;111(18):6708-13. doi: 10.1073/pnas.1314975111. Epub 2014 Apr 23. Proc Natl Acad Sci U S A. 2014. PMID: 24760828 Free PMC article.

3

Quantification of natural killer cell polarization and visualization of synaptic granule externalization by imaging flow cytometry.

Viswanath DI, Mace EM, Hsu HT, Orange JS. Viswanath DI, et al. Among authors: mace em. Clin Immunol. 2017 Apr;177:70-75. doi: 10.1016/j.clim.2016.03.004. Epub 2016 Mar 3. Clin Immunol. 2017. PMID: 26948929 Free PMC article.

4

NK cells converge lytic granules to promote cytotoxicity and prevent bystander killing.

Hsu HT, Mace EM, Carisey AF, Viswanath DI, Christakou AE, Wiklund M, Önfelt B, Orange JS. Hsu HT, et al. Among authors: mace em. J Cell Biol. 2016 Dec 19;215(6):875-889. doi: 10.1083/jcb.201604136. Epub 2016 Nov 30. J Cell Biol. 2016. PMID: 27903610 Free PMC article.

5

Genetic Causes of Human NK Cell Deficiency and Their Effect on NK Cell Subsets.

Mace EM, Orange JS. Mace EM, et al. Front Immunol. 2016 Dec 2;7:545. doi: 10.3389/fimmu.2016.00545. eCollection 2016. Front Immunol. 2016. PMID: 27994588 Free PMC article. Review.

6

A research-driven approach to the identification of novel natural killer cell deficiencies affecting cytotoxic function.

Lam MT, Mace EM, Orange JS. Lam MT, et al. Among authors: mace em. Blood. 2020 Feb 27;135(9):629-637. doi: 10.1182/blood.2019000925. Blood. 2020. PMID: 31945148 Free PMC article. Review.

7

Human PLCG2 haploinsufficiency results in a novel natural killer cell immunodeficiency.

Alinger JB, Mace EM, Porter JR, Mah-Som AY, Daugherty AL, Li S, Throm AA, Pingel JT, Saucier N, Yao A, Chinn IK, Lupski JR, Ehlayel M, Keller M, Bowman GR, Cooper MA, Orange JS, French AR. Alinger JB, et al. Among authors: mace em. J Allergy Clin Immunol. 2024 Jan;153(1):216-229. doi: 10.1016/j.jaci.2023.09.002. Epub 2023 Sep 13. J Allergy Clin Immunol. 2024. PMID: 37714437 Free PMC article.

8

β-Actin G342D as a Cause of NK Cell Deficiency Impairing Lytic Synapse Termination.

Reed AE, Peraza J, van den Haak F, Hernandez ER, Gibbs RA, Chinn IK, Lupski JR, Marchi E, Reshef R, Alobeid B, Mace EM, Orange JS. Reed AE, et al. Among authors: mace em. J Immunol. 2024 Mar 15;212(6):962-973. doi: 10.4049/jimmunol.2300671. J Immunol. 2024. PMID: 38315012 Free PMC article.

9

NK cell lytic granules are highly motile at the immunological synapse and require F-actin for post-degranulation persistence.

Mace EM, Wu WW, Ho T, Mann SS, Hsu HT, Orange JS. Mace EM, et al. J Immunol. 2012 Nov 15;189(10):4870-80. doi: 10.4049/jimmunol.1201296. Epub 2012 Oct 12. J Immunol. 2012. PMID: 23066148 Free PMC article.

10

New views of the human NK cell immunological synapse: recent advances enabled by super- and high-resolution imaging techniques.

Mace EM, Orange JS. Mace EM, et al. Front Immunol. 2013 Jan 9;3:421. doi: 10.3389/fimmu.2012.00421. eCollection 2012. Front Immunol. 2013. PMID: 23316204 Free PMC article.

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