Daub H - Search Results

1

Evaluation of Cereblon-Directing Warheads for the Development of Orally Bioavailable PROTACs.

Actis M, Cresser-Brown J, Caine EA, Steger M, Aggarwal A, Mayasundari A, Murphy N, Valinciute G, Li Y, Fu X, Yang L, Marsh G, Hughes G, Karadogan B, Wheeler D, Norley M, Spain F, Urh M, Roussel MF, Schwalb B, Daub H, Riching KM, Maple H, Nishiguchi G, Rankovic Z. Actis M, et al. Among authors: daub h. J Med Chem. 2025 Jan 15. doi: 10.1021/acs.jmedchem.4c02709. Online ahead of print. J Med Chem. 2025. PMID: 39813384

2

Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε.

Haag A, Němec V, Janovská P, Bartošíková J, Adhikari B, Müller J, Schwalm MP, Čada Š, Ohmayer U, Daub H, Kim Y, Born F, Wolf E, Bryja V, Knapp S. Haag A, et al. Among authors: daub h. J Med Chem. 2025 Jan 9;68(1):506-530. doi: 10.1021/acs.jmedchem.4c02201. Epub 2024 Dec 27. J Med Chem. 2025. PMID: 39729064

3

Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulation.

Swietlik JJ, Bärthel S, Falcomatà C, Fink D, Sinha A, Cheng J, Ebner S, Landgraf P, Dieterich DC, Daub H, Saur D, Meissner F. Swietlik JJ, et al. Among authors: daub h. Nat Commun. 2023 May 8;14(1):2642. doi: 10.1038/s41467-023-38171-8. Nat Commun. 2023. PMID: 37156840 Free PMC article.

4

Time-resolved in vivo ubiquitinome profiling by DIA-MS reveals USP7 targets on a proteome-wide scale.

Steger M, Demichev V, Backman M, Ohmayer U, Ihmor P, Müller S, Ralser M, Daub H. Steger M, et al. Among authors: daub h. Nat Commun. 2021 Sep 13;12(1):5399. doi: 10.1038/s41467-021-25454-1. Nat Commun. 2021. PMID: 34518535 Free PMC article.

5

TOR signaling regulates liquid phase separation of the SMN complex governing snRNP biogenesis.

Schilling M, Prusty AB, Boysen B, Oppermann FS, Riedel YL, Husedzinovic A, Rasouli H, König A, Ramanathan P, Reymann J, Erfle H, Daub H, Fischer U, Gruss OJ. Schilling M, et al. Among authors: daub h. Cell Rep. 2021 Jun 22;35(12):109277. doi: 10.1016/j.celrep.2021.109277. Cell Rep. 2021. PMID: 34161763 Free article.

6

The trimer to monomer transition of Tumor Necrosis Factor-Alpha is a dynamic process that is significantly altered by therapeutic antibodies.

Daub H, Traxler L, Ismajli F, Groitl B, Itzen A, Rant U. Daub H, et al. Sci Rep. 2020 Jun 9;10(1):9265. doi: 10.1038/s41598-020-66123-5. Sci Rep. 2020. PMID: 32518229 Free PMC article.

7

Validation of the Slow Off-Kinetics of Sirtuin-Rearranging Ligands (SirReals) by Means of Label-Free Electrically Switchable Nanolever Technology.

Schiedel M, Daub H, Itzen A, Jung M. Schiedel M, et al. Among authors: daub h. Chembiochem. 2020 Apr 17;21(8):1161-1166. doi: 10.1002/cbic.201900527. Epub 2020 Jan 22. Chembiochem. 2020. PMID: 31692222 Free PMC article.

8

A DNA-Based Biosensor Assay for the Kinetic Characterization of Ion-Dependent Aptamer Folding and Protein Binding.

Ponzo I, Möller FM, Daub H, Matscheko N. Ponzo I, et al. Among authors: daub h. Molecules. 2019 Aug 8;24(16):2877. doi: 10.3390/molecules24162877. Molecules. 2019. PMID: 31398834 Free PMC article.

9

Alternative stable conformation capable of protein misinteraction links tRNA synthetase to peripheral neuropathy.

Blocquel D, Li S, Wei N, Daub H, Sajish M, Erfurth ML, Kooi G, Zhou J, Bai G, Schimmel P, Jordanova A, Yang XL. Blocquel D, et al. Among authors: daub h. Nucleic Acids Res. 2017 Jul 27;45(13):8091-8104. doi: 10.1093/nar/gkx455. Nucleic Acids Res. 2017. PMID: 28531329 Free PMC article.

10

Mps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome Segregation.

Maciejowski J, Drechsler H, Grundner-Culemann K, Ballister ER, Rodriguez-Rodriguez JA, Rodriguez-Bravo V, Jones MJK, Foley E, Lampson MA, Daub H, McAinsh AD, Jallepalli PV. Maciejowski J, et al. Among authors: daub h. Dev Cell. 2017 Apr 24;41(2):143-156.e6. doi: 10.1016/j.devcel.2017.03.025. Dev Cell. 2017. PMID: 28441529 Free PMC article.

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