Larrosa I - Search Results

1

Engineered enzymes for enantioselective nucleophilic aromatic substitutions.

Lister TM, Roberts GW, Hossack EJ, Zhao F, Burke AJ, Johannissen LO, Hardy FJ, Millman AAV, Leys D, Larrosa I, Green AP. Lister TM, et al. Among authors: larrosa i. Nature. 2025 Jan 15. doi: 10.1038/s41586-025-08611-0. Online ahead of print. Nature. 2025. PMID: 39814071

2

Small-Molecule Inhibition of CBX4/7 Hypersensitises Homologous Recombination-Impaired Cancer to Radiation by Compromising CtIP-Mediated DNA End Resection.

Osborne HC, Foster BM, Al-Hazmi H, Meyer S, Larrosa I, Schmidt CK. Osborne HC, et al. Among authors: larrosa i. Cancers (Basel). 2024 Jun 6;16(11):2155. doi: 10.3390/cancers16112155. Cancers (Basel). 2024. PMID: 38893273 Free PMC article.

3

An air- and moisture-stable ruthenium precatalyst for diverse reactivity.

McArthur G, Docherty JH, Hareram MD, Simonetti M, Vitorica-Yrezabal IJ, Douglas JJ, Larrosa I. McArthur G, et al. Among authors: larrosa i. Nat Chem. 2024 Jul;16(7):1141-1150. doi: 10.1038/s41557-024-01481-5. Epub 2024 Apr 3. Nat Chem. 2024. PMID: 38570728 Free PMC article.

4

Unlocking regioselective meta-alkylation with epoxides and oxetanes via dynamic kinetic catalyst control.

Bai PB, Durie A, Wang GW, Larrosa I. Bai PB, et al. Among authors: larrosa i. Nat Commun. 2024 Jan 2;15(1):31. doi: 10.1038/s41467-023-44219-6. Nat Commun. 2024. PMID: 38167324 Free PMC article.

5

Defect-free graphene enhances enzyme delivery to fibroblasts derived from patients with lysosomal storage disorders.

Chen Y, Taufiq T, Zeng N, Lozano N, Karakasidi A, Church H, Jovanovic A, Jones SA, Panigrahi A, Larrosa I, Kostarelos K, Casiraghi C, Vranic S. Chen Y, et al. Among authors: larrosa i. Nanoscale. 2023 Jun 1;15(21):9348-9364. doi: 10.1039/d2nr04971f. Nanoscale. 2023. PMID: 37165691

6

Transition-Metal-Catalyzed C-H Bond Activation for the Formation of C-C Bonds in Complex Molecules.

Docherty JH, Lister TM, Mcarthur G, Findlay MT, Domingo-Legarda P, Kenyon J, Choudhary S, Larrosa I. Docherty JH, et al. Among authors: larrosa i. Chem Rev. 2023 Jun 28;123(12):7692-7760. doi: 10.1021/acs.chemrev.2c00888. Epub 2023 May 10. Chem Rev. 2023. PMID: 37163671 Free PMC article. Review.

7

Improving the sustainability of the ruthenium-catalysed N-directed C-H arylation of arenes with aryl halides.

Findlay MT, Hogg AS, Douglas JJ, Larrosa I. Findlay MT, et al. Among authors: larrosa i. Green Chem. 2023 Mar 7;25(6):2394-2400. doi: 10.1039/d2gc03860a. eCollection 2023 Mar 20. Green Chem. 2023. PMID: 36960441 Free PMC article.

8

Carboxylic Acid Salts as Dual-Function Reagents for Carboxylation and Carbon Isotope Labeling.

Wang S, Larrosa I, Yorimitsu H, Perry GJP. Wang S, et al. Among authors: larrosa i. Angew Chem Int Ed Engl. 2023 Mar 27;62(14):e202218371. doi: 10.1002/anie.202218371. Epub 2023 Feb 26. Angew Chem Int Ed Engl. 2023. PMID: 36746757

9

Organic reaction mechanism classification using machine learning.

Burés J, Larrosa I. Burés J, et al. Among authors: larrosa i. Nature. 2023 Jan;613(7945):689-695. doi: 10.1038/s41586-022-05639-4. Epub 2023 Jan 25. Nature. 2023. PMID: 36697863

10

Ruthenium-Catalyzed Monoselective C-H Methylation and d ₃-Methylation of Arenes.

Hogg A, Wheatley M, Domingo-Legarda P, Carral-Menoyo A, Cottam N, Larrosa I. Hogg A, et al. Among authors: larrosa i. JACS Au. 2022 Oct 21;2(11):2529-2538. doi: 10.1021/jacsau.2c00399. eCollection 2022 Nov 28. JACS Au. 2022. PMID: 36465534 Free PMC article.

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