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A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease.
Lim K, Rutherford EN, Delpiano L, He P, Lin W, Sun D, Van den Boomen DJH, Edgar JR, Bang JH, Predeus A, Teichmann SA, Marioni JC, Matesic LE, Lee JH, Lehner PJ, Marciniak SJ, Rawlins EL, Dickens JA. Lim K, et al. Among authors: marciniak sj. EMBO J. 2025 Jan 15. doi: 10.1038/s44318-024-00328-6. Online ahead of print. EMBO J. 2025. PMID: 39815007
GDF15 antagonism limits severe heart failure and prevents cardiac cachexia.
Takaoka M, Tadross JA, Al-Hadithi ABAK, Zhao X, Villena-Gutiérrez R, Tromp J, Absar S, Au M, Harrison J, Coll AP, Marciniak SJ, Rimmington D, Oliver E, Ibáñez B, Voors AA, O'Rahilly S, Mallat Z, Goodall JC. Takaoka M, et al. Among authors: marciniak sj. Cardiovasc Res. 2024 Dec 31;120(17):2249-2260. doi: 10.1093/cvr/cvae214. Cardiovasc Res. 2024. PMID: 39312445 Free PMC article.
Leveraging the pleural space for anticancer therapies in pleural mesothelioma.
Blyth KG, Adusumilli PS, Astoul P, Darlison L, Lee YCG, Mansfield AS, Marciniak SJ, Maskell N, Panou V, Peikert T, Rahman NM, Zauderer MG, Sterman D, Fennell DA. Blyth KG, et al. Among authors: marciniak sj. Lancet Respir Med. 2024 Jun;12(6):476-483. doi: 10.1016/S2213-2600(24)00111-5. Epub 2024 May 10. Lancet Respir Med. 2024. PMID: 38740045 Review.
Enhancing Drug Delivery Efficacy Through Bilayer Coating of Zirconium-Based Metal-Organic Frameworks: Sustained Release and Improved Chemical Stability and Cellular Uptake for Cancer Therapy.
Liu X, Obacz J, Emanuelli G, Chambers JE, Abreu S, Chen X, Linnane E, Mehta JP, Wheatley AEH, Marciniak SJ, Fairen-Jimenez D. Liu X, et al. Among authors: marciniak sj. Chem Mater. 2024 Apr 11;36(8):3588-3603. doi: 10.1021/acs.chemmater.3c02954. eCollection 2024 Apr 23. Chem Mater. 2024. PMID: 38681089 Free PMC article.
Single-cell transcriptomic analysis of human pleura reveals stromal heterogeneity and informs in vitro models of mesothelioma.
Obacz J, Valer JA, Nibhani R, Adams TS, Schupp JC, Veale N, Lewis-Wade A, Flint J, Hogan J, Aresu G, Coonar AS, Peryt A, Biffi G, Kaminski N, Francies H, Rassl DM, Garnett MJ, Rintoul RC, Marciniak SJ. Obacz J, et al. Among authors: marciniak sj. Eur Respir J. 2024 Jan 25;63(1):2300143. doi: 10.1183/13993003.00143-2023. Print 2024 Jan. Eur Respir J. 2024. PMID: 38212075 Free PMC article.
137 results