Fong TM - Search Results

1

Synthesis and biological evaluation of NK1 antagonists derived from L-tryptophan.

MacLeod AM, Cascieri MA, Merchant KJ, Sadowski S, Hardwicke S, Lewis RT, MacIntyre DE, Metzger JM, Fong TM, Shepheard S, et al. MacLeod AM, et al. Among authors: fong tm. J Med Chem. 1995 Mar 17;38(6):934-41. doi: 10.1021/jm00006a012. J Med Chem. 1995. PMID: 7535362

2

Identification of a series of 3-(benzyloxy)-1-azabicyclo[2.2.2]octane human NK1 antagonists.

Swain CJ, Seward EM, Cascieri MA, Fong TM, Herbert R, MacIntyre DE, Merchant KJ, Owen SN, Owens AP, Sabin V, et al. Swain CJ, et al. Among authors: fong tm. J Med Chem. 1995 Nov 24;38(24):4793-805. doi: 10.1021/jm00024a007. J Med Chem. 1995. PMID: 7490729

3

Interaction of glutamine 165 in the fourth transmembrane segment of the human neurokinin-1 receptor with quinuclidine antagonists.

Fong TM, Yu H, Cascieri MA, Underwood D, Swain CJ, Strader CD. Fong TM, et al. J Biol Chem. 1994 May 27;269(21):14957-61. J Biol Chem. 1994. PMID: 8195129 Free article.

4

Synthesis of functionalized 1,8-naphthyridinones and their evaluation as novel, orally active CB1 receptor inverse agonists.

Debenham JS, Madsen-Duggan CB, Walsh TF, Wang J, Tong X, Doss GA, Lao J, Fong TM, Schaeffer MT, Xiao JC, Huang CR, Shen CP, Feng Y, Marsh DJ, Stribling DS, Shearman LP, Strack AM, MacIntyre DE, Van der Ploeg LH, Goulet MT. Debenham JS, et al. Among authors: fong tm. Bioorg Med Chem Lett. 2006 Feb;16(3):681-5. doi: 10.1016/j.bmcl.2005.10.028. Epub 2005 Nov 2. Bioorg Med Chem Lett. 2006. PMID: 16263284

5

Determination of the amino acid residues in substance P conferring selectivity and specificity for the rat neurokinin receptors.

Cascieri MA, Huang RR, Fong TM, Cheung AH, Sadowski S, Ber E, Strader CD. Cascieri MA, et al. Among authors: fong tm. Mol Pharmacol. 1992 Jun;41(6):1096-9. Mol Pharmacol. 1992. PMID: 1377326

6

Characterization of the binding of a potent, selective, radioiodinated antagonist to the human neurokinin-1 receptor.

Cascieri MA, Ber E, Fong TM, Sadowski S, Bansal A, Swain C, Seward E, Frances B, Burns D, Strader CD. Cascieri MA, et al. Among authors: fong tm. Mol Pharmacol. 1992 Sep;42(3):458-63. Mol Pharmacol. 1992. PMID: 1383685

7

Characterization of the binding of [125I-iodo-histidyl, methyl-Phe7] neurokinin B to the neurokinin-3 receptor.

Sadowski S, Huang RR, Fong TM, Marko O, Cascieri MA. Sadowski S, et al. Among authors: fong tm. Neuropeptides. 1993 Jun;24(6):317-9. doi: 10.1016/0143-4179(93)90001-q. Neuropeptides. 1993. PMID: 7688872

8

The role of histidine 265 in antagonist binding to the neurokinin-1 receptor.

Fong TM, Yu H, Cascieri MA, Underwood D, Swain CJ, Strader CD. Fong TM, et al. J Biol Chem. 1994 Jan 28;269(4):2728-32. J Biol Chem. 1994. PMID: 8300604 Free article.

9

Amino-aromatic interaction between histidine 197 of the neurokinin-1 receptor and CP 96345.

Fong TM, Cascieri MA, Yu H, Bansal A, Swain C, Strader CD. Fong TM, et al. Nature. 1993 Mar 25;362(6418):350-3. doi: 10.1038/362350a0. Nature. 1993. PMID: 8384323

10

Molecular characterization of a common binding site for small molecules within the transmembrane domain of G-protein coupled receptors.

Cascieri MA, Fong TM, Strader CD. Cascieri MA, et al. Among authors: fong tm. J Pharmacol Toxicol Methods. 1995 Aug;33(4):179-85. doi: 10.1016/1056-8719(95)00002-y. J Pharmacol Toxicol Methods. 1995. PMID: 8527825 Review.

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