Nijhuis M - Search Results

1

Rapid changes in human immunodeficiency virus type 1 RNA load and appearance of drug-resistant virus populations in persons treated with lamivudine (3TC).

Schuurman R, Nijhuis M, van Leeuwen R, Schipper P, de Jong D, Collis P, Danner SA, Mulder J, Loveday C, Christopherson C, et al. Schuurman R, et al. Among authors: nijhuis m. J Infect Dis. 1995 Jun;171(6):1411-9. doi: 10.1093/infdis/171.6.1411. J Infect Dis. 1995. PMID: 7539472

2

Sensitive procedure for the amplification of HIV-1 RNA using a combined reverse-transcription and amplification reaction.

Nijhuis M, Boucher CA, Schuurman R. Nijhuis M, et al. Biotechniques. 1995 Aug;19(2):178-80, 182. Biotechniques. 1995. PMID: 8527130 No abstract available.

3

Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.

Back NK, Nijhuis M, Keulen W, Boucher CA, Oude Essink BO, van Kuilenburg AB, van Gennip AH, Berkhout B. Back NK, et al. Among authors: nijhuis m. EMBO J. 1996 Aug 1;15(15):4040-9. EMBO J. 1996. PMID: 8670908 Free PMC article.

4

Human immunodeficiency virus type 1 drug susceptibility determination by using recombinant viruses generated from patient sera tested in a cell-killing assay.

Boucher CA, Keulen W, van Bommel T, Nijhuis M, de Jong D, de Jong MD, Schipper P, Back NK. Boucher CA, et al. Among authors: nijhuis m. Antimicrob Agents Chemother. 1996 Oct;40(10):2404-9. doi: 10.1128/AAC.40.10.2404. Antimicrob Agents Chemother. 1996. PMID: 8891152 Free PMC article.

5

Reverse transcriptase fidelity and HIV-1 variation.

Keulen W, Nijhuis M, Schuurman R, Berkhout B, Boucher C. Keulen W, et al. Among authors: nijhuis m. Science. 1997 Jan 10;275(5297):229; author reply 230-1. Science. 1997. PMID: 8999550 No abstract available.

6

Lamivudine-resistant human immunodeficiency virus type 1 variants (184V) require multiple amino acid changes to become co-resistant to zidovudine in vivo.

Nijhuis M, Schuurman R, de Jong D, van Leeuwen R, Lange J, Danner S, Keulen W, de Groot T, Boucher CA. Nijhuis M, et al. J Infect Dis. 1997 Aug;176(2):398-405. doi: 10.1086/514056. J Infect Dis. 1997. PMID: 9237704

7

Efficient inhibition of both syncytium-inducing and non-syncytium-inducing wild-type HIV-1 by lamivudine in vivo.

van 't Wout AB, Ran LJ, Nijhuis M, Tijnagel JM, de Groot T, van Leeuwen R, Boucher CA, Schuitemaker H, Schuurman R. van 't Wout AB, et al. Among authors: nijhuis m. AIDS. 1998 Jul 9;12(10):1169-76. doi: 10.1097/00002030-199810000-00009. AIDS. 1998. PMID: 9677166

8

Efficacy of adding indinavir to previous reverse transcriptase nucleoside analogues in relation to genotypic and phenotypic resistance development in advanced HIV-1-infected patients.

Ruiz L, Nijhuis M, Boucher C, Puig T, Bonjoch A, Martínez-Picado J, Marfil S, de Jong D, Burger D, Arnó A, Balagué M, Clotet B. Ruiz L, et al. Among authors: nijhuis m. J Acquir Immune Defic Syndr Hum Retrovirol. 1998 Sep 1;19(1):19-28. doi: 10.1097/00042560-199809010-00003. J Acquir Immune Defic Syndr Hum Retrovirol. 1998. PMID: 9732064 Clinical Trial.

9

Stochastic processes strongly influence HIV-1 evolution during suboptimal protease-inhibitor therapy.

Nijhuis M, Boucher CA, Schipper P, Leitner T, Schuurman R, Albert J. Nijhuis M, et al. Proc Natl Acad Sci U S A. 1998 Nov 24;95(24):14441-6. doi: 10.1073/pnas.95.24.14441. Proc Natl Acad Sci U S A. 1998. PMID: 9826719 Free PMC article.

10

Increased fitness of drug resistant HIV-1 protease as a result of acquisition of compensatory mutations during suboptimal therapy.

Nijhuis M, Schuurman R, de Jong D, Erickson J, Gustchina E, Albert J, Schipper P, Gulnik S, Boucher CA. Nijhuis M, et al. AIDS. 1999 Dec 3;13(17):2349-59. doi: 10.1097/00002030-199912030-00006. AIDS. 1999. PMID: 10597776

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