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2',5'-Bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''- oxathiole-2'',2'-dioxide)pyrimidine (TSAO) nucleoside analogues: highlyselective inhibitors of human immunodeficiency virus type 1 that are targeted at the viral reverse transcriptase.
Balzarini J, Pérez-Pérez MJ, San-Félix A, Schols D, Perno CF, Vandamme AM, Camarasa MJ, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Proc Natl Acad Sci U S A. 1992 May 15;89(10):4392-6. doi: 10.1073/pnas.89.10.4392. Proc Natl Acad Sci U S A. 1992. PMID: 1374900 Free PMC article.
Kinetics of inhibition of endogenous human immunodeficiency virus type 1 reverse transcription by 2',3'-dideoxynucleoside 5'-triphosphate, tetrahydroimidazo-[4,5,1-jk][1,4]-benzodiazepin-2(1H)-thion e, and 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives.
Debyser Z, Vandamme AM, Pauwels R, Baba M, Desmyter J, De Clercq E. Debyser Z, et al. Among authors: de clercq e. J Biol Chem. 1992 Jun 15;267(17):11769-76. J Biol Chem. 1992. PMID: 1376311 Free article.
Kinetics of inhibition of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase by the novel HIV-1-specific nucleoside analogue [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5 "- (4"-amino-1",2"-oxathiole-2",2"-dioxide)thymine (TSAO-T).
Balzarini J, Pérez-Pérez MJ, San-Félix A, Camarasa MJ, Bathurst IC, Barr PJ, De Clercq E. Balzarini J, et al. Among authors: de clercq e. J Biol Chem. 1992 Jun 15;267(17):11831-8. J Biol Chem. 1992. PMID: 1376314 Free article.
[2',5'-Bis-O-(tert-butyldimethylsilyl)]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide) (TSAO) derivatives of purine and pyrimidinenucleosides as potent and selective inhibitors of human immunodeficiency virus type 1.
Balzarini J, Pérez-Pérez MJ, San-Félix A, Velazquez S, Camarasa MJ, De Clercq E. Balzarini J, et al. Among authors: de clercq e. Antimicrob Agents Chemother. 1992 May;36(5):1073-80. doi: 10.1128/AAC.36.5.1073. Antimicrob Agents Chemother. 1992. PMID: 1510396 Free PMC article.
Differential inhibitory effects of sulfated polysaccharides and polymers on the replication of various myxoviruses and retroviruses, depending on the composition of the target amino acid sequences of the viral envelope glycoproteins.
Hosoya M, Balzarini J, Shigeta S, De Clercq E. Hosoya M, et al. Among authors: de clercq e. Antimicrob Agents Chemother. 1991 Dec;35(12):2515-20. doi: 10.1128/AAC.35.12.2515. Antimicrob Agents Chemother. 1991. PMID: 1725692 Free PMC article.
2,294 results