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Isolation, structure, and absolute stereochemistry of platensimycin, a broad spectrum antibiotic discovered using an antisense differential sensitivity strategy.
Singh SB, Jayasuriya H, Ondeyka JG, Herath KB, Zhang C, Zink DL, Tsou NN, Ball RG, Basilio A, Genilloud O, Diez MT, Vicente F, Pelaez F, Young K, Wang J. Singh SB, et al. Among authors: ball rg. J Am Chem Soc. 2006 Sep 13;128(36):11916-20. doi: 10.1021/ja062232p. J Am Chem Soc. 2006. PMID: 16953632
Coelomycin, a highly substituted 2,6-dioxo-pyrazine fungal metabolite antibacterial agent discovered by Staphylococcus aureus fitness test profiling.
Goetz MA, Zhang C, Zink DL, Arocho M, Vicente F, Bills GF, Polishook J, Dorso K, Onishi R, Gill C, Hickey E, Lee S, Ball R, Skwish S, Donald RG, Phillips JW, Singh SB. Goetz MA, et al. Among authors: ball r. J Antibiot (Tokyo). 2010 Aug;63(8):512-8. doi: 10.1038/ja.2010.86. Epub 2010 Jul 28. J Antibiot (Tokyo). 2010. PMID: 20664605
Isolation and structure elucidation of parnafungins, antifungal natural products that inhibit mRNA polyadenylation.
Parish CA, Smith SK, Calati K, Zink D, Wilson K, Roemer T, Jiang B, Xu D, Bills G, Platas G, Peláez F, Díez MT, Tsou N, McKeown AE, Ball RG, Powles MA, Yeung L, Liberator P, Harris G. Parish CA, et al. Among authors: ball rg. J Am Chem Soc. 2008 Jun 4;130(22):7060-6. doi: 10.1021/ja711209p. Epub 2008 May 8. J Am Chem Soc. 2008. PMID: 18461935
Highly potent, orally active diester macrocyclic human renin inhibitors.
Weber AE, Steiner MG, Krieter PA, Colletti AE, Tata JR, Halgren TA, Ball RG, Doyle JJ, Schorn TW, Stearns RA, et al. Weber AE, et al. Among authors: ball rg. J Med Chem. 1992 Oct 16;35(21):3755-73. doi: 10.1021/jm00099a004. J Med Chem. 1992. PMID: 1433190
69 results