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Heterozygosity for a deletion in the CKR-5 gene leads to prolonged AIDS-free survival and slower CD4 T-cell decline in a cohort of HIV-seropositive individuals.
Eugen-Olsen J, Iversen AK, Garred P, Koppelhus U, Pedersen C, Benfield TL, Sorensen AM, Katzenstein T, Dickmeiss E, Gerstoft J, Skinhøj P, Svejgaard A, Nielsen JO, Hofmann B. Eugen-Olsen J, et al. Among authors: hofmann b. AIDS. 1997 Mar;11(3):305-10. doi: 10.1097/00002030-199703110-00007. AIDS. 1997. PMID: 9147421
HIV-infected individuals with the CCR delta32/CCR5 genotype have lower HIV RNA levels and higher CD4 cell counts in the early years of the infection than do patients with the wild type. Copenhagen AIDS Cohort Study Group.
Katzenstein TL, Eugen-Olsen J, Hofmann B, Benfield T, Pedersen C, Iversen AK, Sørensen AM, Garred P, Koppelhus U, Svejgaard A, Gerstoft J. Katzenstein TL, et al. Among authors: hofmann b. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Sep 1;16(1):10-4. doi: 10.1097/00042560-199709010-00002. J Acquir Immune Defic Syndr Hum Retrovirol. 1997. PMID: 9377119
718 results