Altomare DA - Search Results

1

Cloning, chromosomal localization and expression analysis of the mouse Akt2 oncogene.

Altomare DA, Guo K, Cheng JQ, Sonoda G, Walsh K, Testa JR. Altomare DA, et al. Oncogene. 1995 Sep 21;11(6):1055-60. Oncogene. 1995. PMID: 7566964

2

AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth.

Altomare DA, Wang HQ, Skele KL, De Rienzo A, Klein-Szanto AJ, Godwin AK, Testa JR. Altomare DA, et al. Oncogene. 2004 Jul 29;23(34):5853-7. doi: 10.1038/sj.onc.1207721. Oncogene. 2004. PMID: 15208673

3

Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells.

Wang HQ, Altomare DA, Skele KL, Poulikakos PI, Kuhajda FP, Di Cristofano A, Testa JR. Wang HQ, et al. Among authors: altomare da. Oncogene. 2005 May 19;24(22):3574-82. doi: 10.1038/sj.onc.1208463. Oncogene. 2005. PMID: 15806173

4

Human and mouse mesotheliomas exhibit elevated AKT/PKB activity, which can be targeted pharmacologically to inhibit tumor cell growth.

Altomare DA, You H, Xiao GH, Ramos-Nino ME, Skele KL, De Rienzo A, Jhanwar SC, Mossman BT, Kane AB, Testa JR. Altomare DA, et al. Oncogene. 2005 Sep 8;24(40):6080-9. doi: 10.1038/sj.onc.1208744. Oncogene. 2005. PMID: 15897870

5

Perturbations of the AKT signaling pathway in human cancer.

Altomare DA, Testa JR. Altomare DA, et al. Oncogene. 2005 Nov 14;24(50):7455-64. doi: 10.1038/sj.onc.1209085. Oncogene. 2005. PMID: 16288292 Review.

6

Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.

Cheng JQ, Ruggeri B, Klein WM, Sonoda G, Altomare DA, Watson DK, Testa JR. Cheng JQ, et al. Among authors: altomare da. Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3636-41. doi: 10.1073/pnas.93.8.3636. Proc Natl Acad Sci U S A. 1996. PMID: 8622988 Free PMC article.

7

Chromosome mapping of the mouse Akt2 gene and Akt2 pseudogene.

Altomare DA, Kozak CA, Sonoda G, Testa JR. Altomare DA, et al. Cytogenet Cell Genet. 1996;74(4):248-51. doi: 10.1159/000134426. Cytogenet Cell Genet. 1996. PMID: 8976376

8

Transforming activity and mitosis-related expression of the AKT2 oncogene: evidence suggesting a link between cell cycle regulation and oncogenesis.

Cheng JQ, Altomare DA, Klein MA, Lee WC, Kruh GD, Lissy NA, Testa JR. Cheng JQ, et al. Among authors: altomare da. Oncogene. 1997 Jun 12;14(23):2793-801. doi: 10.1038/sj.onc.1201121. Oncogene. 1997. PMID: 9190895

9

Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin.

Altomare DA, Lyons GE, Mitsuuchi Y, Cheng JQ, Testa JR. Altomare DA, et al. Oncogene. 1998 May 7;16(18):2407-11. doi: 10.1038/sj.onc.1201750. Oncogene. 1998. PMID: 9620559

10

AKT2 is frequently upregulated in HER-2/neu-positive breast cancers and may contribute to tumor aggressiveness by enhancing cell survival.

Bacus SS, Altomare DA, Lyass L, Chin DM, Farrell MP, Gurova K, Gudkov A, Testa JR. Bacus SS, et al. Among authors: altomare da. Oncogene. 2002 May 16;21(22):3532-40. doi: 10.1038/sj.onc.1205438. Oncogene. 2002. PMID: 12032855

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