Townes TM - Search Results

1

Mouse model of human beta zero thalassemia: targeted deletion of the mouse beta maj- and beta min-globin genes in embryonic stem cells.

Ciavatta DJ, Ryan TM, Farmer SC, Townes TM. Ciavatta DJ, et al. Among authors: townes tm. Proc Natl Acad Sci U S A. 1995 Sep 26;92(20):9259-63. doi: 10.1073/pnas.92.20.9259. Proc Natl Acad Sci U S A. 1995. PMID: 7568113 Free PMC article.

2

Correction of a mouse model of sickle cell disease: lentiviral/antisickling beta-globin gene transduction of unmobilized, purified hematopoietic stem cells.

Levasseur DN, Ryan TM, Pawlik KM, Townes TM. Levasseur DN, et al. Among authors: townes tm. Blood. 2003 Dec 15;102(13):4312-9. doi: 10.1182/blood-2003-04-1251. Epub 2003 Aug 21. Blood. 2003. PMID: 12933581 Free article.

3

Correction of sickle cell disease by homologous recombination in embryonic stem cells.

Wu LC, Sun CW, Ryan TM, Pawlik KM, Ren J, Townes TM. Wu LC, et al. Among authors: townes tm. Blood. 2006 Aug 15;108(4):1183-8. doi: 10.1182/blood-2006-02-004812. Epub 2006 Apr 25. Blood. 2006. PMID: 16638928 Free PMC article.

4

Human beta-globin locus control region: analysis of the 5' DNase I hypersensitive site HS 2 in transgenic mice.

Caterina JJ, Ryan TM, Pawlik KM, Palmiter RD, Brinster RL, Behringer RR, Townes TM. Caterina JJ, et al. Among authors: townes tm. Proc Natl Acad Sci U S A. 1991 Mar 1;88(5):1626-30. doi: 10.1073/pnas.88.5.1626. Proc Natl Acad Sci U S A. 1991. PMID: 2000371 Free PMC article.

5

A single erythroid-specific DNase I super-hypersensitive site activates high levels of human beta-globin gene expression in transgenic mice.

Ryan TM, Behringer RR, Martin NC, Townes TM, Palmiter RD, Brinster RL. Ryan TM, et al. Among authors: townes tm. Genes Dev. 1989 Mar;3(3):314-23. doi: 10.1101/gad.3.3.314. Genes Dev. 1989. PMID: 2721958 Free article.

6

High-level erythroid expression of human alpha-globin genes in transgenic mice.

Ryan TM, Behringer RR, Townes TM, Palmiter RD, Brinster RL. Ryan TM, et al. Among authors: townes tm. Proc Natl Acad Sci U S A. 1989 Jan;86(1):37-41. doi: 10.1073/pnas.86.1.37. Proc Natl Acad Sci U S A. 1989. PMID: 2911581 Free PMC article.

7

Knockout-transgenic mouse model of sickle cell disease.

Ryan TM, Ciavatta DJ, Townes TM. Ryan TM, et al. Among authors: townes tm. Science. 1997 Oct 31;278(5339):873-6. doi: 10.1126/science.278.5339.873. Science. 1997. PMID: 9346487

8

Human gamma-globin gene promoter element regulates human beta-globin gene developmental specificity.

Ryan TM, Sun CW, Ren J, Townes TM. Ryan TM, et al. Among authors: townes tm. Nucleic Acids Res. 2000 Jul 15;28(14):2736-40. doi: 10.1093/nar/28.14.2736. Nucleic Acids Res. 2000. PMID: 10908330 Free PMC article.

9

Mouse model of congenital polycythemia: Homologous replacement of murine gene by mutant human erythropoietin receptor gene.

Divoky V, Liu Z, Ryan TM, Prchal JF, Townes TM, Prchal JT. Divoky V, et al. Among authors: townes tm. Proc Natl Acad Sci U S A. 2001 Jan 30;98(3):986-91. doi: 10.1073/pnas.98.3.986. Proc Natl Acad Sci U S A. 2001. PMID: 11158582 Free PMC article.

10

A recombinant human hemoglobin with anti-sickling properties greater than fetal hemoglobin.

Levasseur DN, Ryan TM, Reilly MP, McCune SL, Asakura T, Townes TM. Levasseur DN, et al. Among authors: townes tm. J Biol Chem. 2004 Jun 25;279(26):27518-24. doi: 10.1074/jbc.M402578200. Epub 2004 Apr 14. J Biol Chem. 2004. PMID: 15084588 Free article.

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