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Phase I and pharmacokinetic study of continuous twice weekly intravenous administration of Cilengitide (EMD 121974), a novel inhibitor of the integrins alphavbeta3 and alphavbeta5 in patients with advanced solid tumours.
Eskens FA, Dumez H, Hoekstra R, Perschl A, Brindley C, Böttcher S, Wynendaele W, Drevs J, Verweij J, van Oosterom AT. Eskens FA, et al. Eur J Cancer. 2003 May;39(7):917-26. doi: 10.1016/s0959-8049(03)00057-1. Eur J Cancer. 2003. PMID: 12706360 Clinical Trial.
Phase I and pharmacokinetic study of irinotecan in combination with R115777, a farnesyl protein transferase inhibitor.
Sparreboom A, Kehrer DF, Mathijssen RH, Xie R, de Jonge MJ, de Bruijn P, Planting AS, Eskens FA, Verheij C, de Heus G, Klaren A, Zhang S, Verhaeghe T, Palmer PA, Verweij J. Sparreboom A, et al. Among authors: eskens fa. Br J Cancer. 2004 Apr 19;90(8):1508-15. doi: 10.1038/sj.bjc.6601732. Br J Cancer. 2004. PMID: 15083177 Free PMC article. Clinical Trial.
Phase I and pharmacokinetic study of the polyamine synthesis inhibitor SAM486A in combination with 5-fluorouracil/leucovorin in metastatic colorectal cancer.
van Zuylen L, Bridgewater J, Sparreboom A, Eskens FA, de Bruijn P, Sklenar I, Planting AS, Choi L, Bootle D, Mueller C, Ledermann JA, Verweij J. van Zuylen L, et al. Among authors: eskens fa. Clin Cancer Res. 2004 Mar 15;10(6):1949-55. doi: 10.1158/1078-0432.ccr-02-0995. Clin Cancer Res. 2004. PMID: 15041711 Free article. Clinical Trial.
Phase I and pharmacokinetic study of oral irinotecan given once daily for 5 days every 3 weeks in combination with capecitabine in patients with solid tumors.
Soepenberg O, Dumez H, Verweij J, Semiond D, deJonge MJ, Eskens FA, ter Steeg J, Selleslach J, Assadourian S, Sanderink GJ, Sparreboom A, van Oosterom AT. Soepenberg O, et al. Among authors: eskens fa. J Clin Oncol. 2005 Feb 1;23(4):889-98. doi: 10.1200/JCO.2005.01.008. J Clin Oncol. 2005. PMID: 15681535 Clinical Trial.
Phase I safety, pharmacokinetic, and pharmacodynamic study of the thrombospondin-1-mimetic angiogenesis inhibitor ABT-510 in patients with advanced cancer.
Hoekstra R, de Vos FY, Eskens FA, Gietema JA, van der Gaast A, Groen HJ, Knight RA, Carr RA, Humerickhouse RA, Verweij J, de Vries EG. Hoekstra R, et al. Among authors: eskens fa. J Clin Oncol. 2005 Aug 1;23(22):5188-97. doi: 10.1200/JCO.2005.05.013. J Clin Oncol. 2005. PMID: 16051960 Clinical Trial.
138 results