Witiak DT - Search Results

1

Beta-lapachone-mediated apoptosis in human promyelocytic leukemia (HL-60) and human prostate cancer cells: a p53-independent response.

Planchon SM, Wuerzberger S, Frydman B, Witiak DT, Hutson P, Church DR, Wilding G, Boothman DA. Planchon SM, et al. Among authors: witiak dt. Cancer Res. 1995 Sep 1;55(17):3706-11. Cancer Res. 1995. PMID: 7641180 Free PMC article.

2

Induction of DNA topoisomerase II-mediated DNA cleavage by beta-lapachone and related naphthoquinones.

Frydman B, Marton LJ, Sun JS, Neder K, Witiak DT, Liu AA, Wang HM, Mao Y, Wu HY, Sanders MM, Liu LF. Frydman B, et al. Among authors: witiak dt. Cancer Res. 1997 Feb 15;57(4):620-7. Cancer Res. 1997. PMID: 9044837

3

Comparative metabolism in vitro of a novel carcinogenic polycyclic aromatic hydrocarbon, 1,2,3,4-tetrahydro-7,12-dimethylbenz[a]anthracene, and its two regioisomeric B-ring fluoro analogues.

Rinderle SJ, Black SD, Sharma PK, Witiak DT. Rinderle SJ, et al. Among authors: witiak dt. Cancer Res. 1992 Jun 1;52(11):3035-42. Cancer Res. 1992. PMID: 1591719

4

Potent antiplatelet effects of cyclic clofibric acid (CPIB) analogs on human platelets.

Romstedt KJ, Kim SU, Witiak DT, Newman HA, Feller DR. Romstedt KJ, et al. Among authors: witiak dt. Thromb Res. 1989 May 15;54(4):289-99. doi: 10.1016/0049-3848(89)90087-x. Thromb Res. 1989. PMID: 2503906

5

Mono and bis(bioreductive) alkylating agents: synthesis and antitumor activities in a B16 melanoma model.

Witiak DT, Loper JT, Ananthan S, Almerico AM, Verhoef VL, Filppi JA. Witiak DT, et al. J Med Chem. 1989 Jul;32(7):1636-42. doi: 10.1021/jm00127a039. J Med Chem. 1989. PMID: 2738896

6

Dioxopiperazines: chemistry and biology.

Witiak DT, Wei Y. Witiak DT, et al. Prog Drug Res. 1990;35:249-363. doi: 10.1007/978-3-0348-7133-4_7. Prog Drug Res. 1990. PMID: 2290982 Review. No abstract available.

7

Synthetic aci-reductones: 3,4-dihydroxy-2H-1-benzopyran-2-ones and their cis- and trans-4a,5,6,7,8,8a-hexahydro diastereomers. Antiaggregatory, antilipidemic, and redox properties compared to those of the 4-substituted 2-hydroxytetronic acids.

Witiak DT, Kim SK, Tehim AK, Sternitzke KD, McCreery RL, Kim SU, Feller DR, Romstedt KJ, Kamanna VS, Newman HA. Witiak DT, et al. J Med Chem. 1988 Jul;31(7):1437-45. doi: 10.1021/jm00402a032. J Med Chem. 1988. PMID: 3133477

8

Modulation of carcinogenicity in 1,2,3,4-tetrahydro-7,12- dimethylbenz[a]anthracene (THDMBA) by fluorine substitution: crystal structures of the 5- and 6-fluoro regioisomers.

Black SD, Sharma PK, Gallucci JC, Blackburn AC, Downs JW, Rinderle SJ, Witiak DT. Black SD, et al. Among authors: witiak dt. Carcinogenesis. 1992 Aug;13(8):1337-43. doi: 10.1093/carcin/13.8.1337. Carcinogenesis. 1992. PMID: 1499085

9

Structure of 6-fluoro-1,2,3,4,7,12-hexahydro-7-methyl-12-methylene- benz[a]anthracene.

Gallucci JC, Sharma PK, Black SD, Rinderle SJ, Witiak DT. Gallucci JC, et al. Among authors: witiak dt. Acta Crystallogr C. 1993 Oct 15;49 ( Pt 10):1868-71. doi: 10.1107/s0108270193003713. Acta Crystallogr C. 1993. PMID: 8297535

10

Mouse skin tumor initiating activity of fluorinated derivatives of 1,2,3,4-tetrahydro-7,12-dimethylbenz[a]anthracene.

Nair RV, Walker SE, Sharma PK, Witiak DT, DiGiovanni J. Nair RV, et al. Among authors: witiak dt. Chem Res Toxicol. 1992 Mar-Apr;5(2):153-6. doi: 10.1021/tx00026a002. Chem Res Toxicol. 1992. PMID: 1643244 No abstract available.

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