de Hon FD - Search Results

1

Leucine-58 in the putative 5th helical region of human interleukin (IL)-6 is important for activation of the IL-6 signal transducer, gp130.

de Hon FD, Klaasse Bos HK, Ebeling SB, Grötzinger J, Kurapkat G, Rose-John S, Aarden LA, Brakenhoff JP. de Hon FD, et al. FEBS Lett. 1995 Aug 7;369(2-3):187-91. doi: 10.1016/0014-5793(95)00741-q. FEBS Lett. 1995. PMID: 7649255 Free article.

2

Development of human IL-6 receptor antagonists.

Brakenhoff JP, de Hon FD, Aarden LA. Brakenhoff JP, et al. Among authors: de hon fd. Ann N Y Acad Sci. 1995 Jul 21;762:129-34; discussion 135. doi: 10.1111/j.1749-6632.1995.tb32321.x. Ann N Y Acad Sci. 1995. PMID: 7668524 Review.

3

Development of an interleukin (IL) 6 receptor antagonist that inhibits IL-6-dependent growth of human myeloma cells.

de Hon FD, Ehlers M, Rose-John S, Ebeling SB, Bos HK, Aarden LA, Brakenhoff JP. de Hon FD, et al. J Exp Med. 1994 Dec 1;180(6):2395-400. doi: 10.1084/jem.180.6.2395. J Exp Med. 1994. PMID: 7964514 Free PMC article.

4

Development of a human interleukin-6 receptor antagonist.

Brakenhoff JP, de Hon FD, Fontaine V, ten Boekel E, Schooltink H, Rose-John S, Heinrich PC, Content J, Aarden LA. Brakenhoff JP, et al. Among authors: de hon fd. J Biol Chem. 1994 Jan 7;269(1):86-93. J Biol Chem. 1994. PMID: 8276883 Free article.

5

Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction.

Ehlers M, Grötzinger J, deHon FD, Müllberg J, Brakenhoff JP, Liu J, Wollmer A, Rose-John S. Ehlers M, et al. J Immunol. 1994 Aug 15;153(4):1744-53. J Immunol. 1994. PMID: 7519211

6

Functional distinction of two regions of human interleukin 6 important for signal transduction via gp130.

de Hon FD, ten Boekel E, Herrman J, Clement C, Ehlers M, Taga T, Yasukawa K, Ohsugi Y, Kishimoto T, Rose-John S, et al. de Hon FD, et al. Cytokine. 1995 Jul;7(5):398-407. doi: 10.1006/cyto.1995.0055. Cytokine. 1995. PMID: 7578977

7

Combining two mutations of human interleukin-6 that affect gp130 activation results in a potent interleukin-6 receptor antagonist on human myeloma cells.

Ehlers M, de Hon FD, Bos HK, Horsten U, Kurapkat G, van De Leur HS, Grötzinger J, Wollmer A, Brakenhoff JP, Rose-John S. Ehlers M, et al. Among authors: de hon fd. J Biol Chem. 1995 Apr 7;270(14):8158-63. doi: 10.1074/jbc.270.14.8158. J Biol Chem. 1995. PMID: 7713920 Free article.

8

Residues 77-95 of the human interleuken-6 protein are responsible for receptor binding and residues 41-56 for signal transduction.

Ehlers M, Grötzinger J, de Hon FD, Müllberg J, Brakenhoff JP, Wollmer A, Rose-John S. Ehlers M, et al. Among authors: de hon fd. Ann N Y Acad Sci. 1995 Jul 21;762:400-2. doi: 10.1111/j.1749-6632.1995.tb32347.x. Ann N Y Acad Sci. 1995. PMID: 7668541 No abstract available.

9

Aqueous humor interleukin-6 levels in uveitis.

Murray PI, Hoekzema R, van Haren MA, de Hon FD, Kijlstra A. Murray PI, et al. Among authors: de hon fd. Invest Ophthalmol Vis Sci. 1990 May;31(5):917-20. Invest Ophthalmol Vis Sci. 1990. PMID: 2335453

10

Indomethacin increases the sensitivity of the monocyte migration inhibition assay.

Van der Gaag R, Broersma L, De Hon FD, Van Haren MA, Hoekzema R. Van der Gaag R, et al. Among authors: de hon fd. J Immunol Methods. 1991 Jan 24;136(1):69-76. doi: 10.1016/0022-1759(91)90251-a. J Immunol Methods. 1991. PMID: 1847398

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