Dutschman GE - Search Results

1

A single conservative amino acid substitution in the reverse transcriptase of human immunodeficiency virus-1 confers resistance to (+)-(5S)-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo[4,5, 1- jk][1,4]benzodiazepin-2(1H)-thione (TIBO R82150).

Mellors JW, Im GJ, Tramontano E, Winkler SR, Medina DJ, Dutschman GE, Bazmi HZ, Piras G, Gonzalez CJ, Cheng YC. Mellors JW, et al. Among authors: dutschman ge. Mol Pharmacol. 1993 Jan;43(1):11-6. Mol Pharmacol. 1993. PMID: 7678690

2

In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase.

Mellors JW, Dutschman GE, Im GJ, Tramontano E, Winkler SR, Cheng YC. Mellors JW, et al. Among authors: dutschman ge. Mol Pharmacol. 1992 Mar;41(3):446-51. Mol Pharmacol. 1992. PMID: 1372083

3

Reverse transcriptase activity of hepatitis B virus (HBV) DNA polymerase within core capsid: interaction with deoxynucleoside triphosphates and anti-HBV L-deoxynucleoside analog triphosphates.

Lam W, Li Y, Liou JY, Dutschman GE, Cheng YC. Lam W, et al. Among authors: dutschman ge. Mol Pharmacol. 2004 Feb;65(2):400-6. doi: 10.1124/mol.65.2.400. Mol Pharmacol. 2004. PMID: 14742682

4

Action of uracil analogs on human immunodeficiency virus type 1 and its reverse transcriptase.

Piras G, Dutschman GE, Im GJ, Pan BC, Chu SH, Cheng YC. Piras G, et al. Among authors: dutschman ge. Antimicrob Agents Chemother. 1995 Feb;39(2):539-41. doi: 10.1128/AAC.39.2.539. Antimicrob Agents Chemother. 1995. PMID: 7537030 Free PMC article.

5

Human immunodeficiency virus reverse transcriptase. General properties and its interactions with nucleoside triphosphate analogs.

Cheng YC, Dutschman GE, Bastow KF, Sarngadharan MG, Ting RY. Cheng YC, et al. Among authors: dutschman ge. J Biol Chem. 1987 Feb 15;262(5):2187-9. J Biol Chem. 1987. PMID: 2434477 Free article.

6

Inhibitory action of 10-deazaaminopterins and their polyglutamates on human thymidylate synthase.

Ueda T, Dutschman GE, Nair MG, Degraw JI, Sirotnak FM, Cheng YC. Ueda T, et al. Among authors: dutschman ge. Mol Pharmacol. 1986 Aug;30(2):149-53. Mol Pharmacol. 1986. PMID: 2426568

7

Antiviral activity of 2',3'-dideoxy-beta-L-5-fluorocytidine (beta-L-FddC) and 2',3'-dideoxy-beta-L-cytidine (beta-L-ddC) against hepatitis B virus and human immunodeficiency virus type 1 in vitro.

Lin TS, Luo MZ, Liu MC, Pai SB, Dutschman GE, Cheng YC. Lin TS, et al. Among authors: dutschman ge. Biochem Pharmacol. 1994 Jan 20;47(2):171-4. doi: 10.1016/0006-2952(94)90002-7. Biochem Pharmacol. 1994. PMID: 8304960

8

Time-dependent action of 5-propyl deoxyuridine as antiherpes simplex virus type 1 and type 2 agents.

Cheng YC, Grill S, Dutschman G. Cheng YC, et al. Biochem Pharmacol. 1979 Dec 15;28(24):3529-32. doi: 10.1016/0006-2952(79)90396-4. Biochem Pharmacol. 1979. PMID: 231448 No abstract available.

9

The biochemical basis for the differential anti-human immunodeficiency virus activity of two cis enantiomers of 2',3'-dideoxy-3'-thiacytidine.

Skalski V, Chang CN, Dutschman G, Cheng YC. Skalski V, et al. J Biol Chem. 1993 Nov 5;268(31):23234-8. J Biol Chem. 1993. PMID: 7693686 Free article.

10

Assessment of the effect of phosphorylated metabolites of anti-human immunodeficiency virus and anti-hepatitis B virus pyrimidine analogs on the behavior of human deoxycytidylate deaminase.

Liou JY, Krishnan P, Hsieh CC, Dutschman GE, Cheng YC. Liou JY, et al. Among authors: dutschman ge. Mol Pharmacol. 2003 Jan;63(1):105-10. doi: 10.1124/mol.63.1.105. Mol Pharmacol. 2003. PMID: 12488542

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