Piras G - Search Results

1

A single conservative amino acid substitution in the reverse transcriptase of human immunodeficiency virus-1 confers resistance to (+)-(5S)-4,5,6,7-tetrahydro-5-methyl-6-(3-methyl-2-butenyl)imidazo[4,5, 1- jk][1,4]benzodiazepin-2(1H)-thione (TIBO R82150).

Mellors JW, Im GJ, Tramontano E, Winkler SR, Medina DJ, Dutschman GE, Bazmi HZ, Piras G, Gonzalez CJ, Cheng YC. Mellors JW, et al. Among authors: piras g. Mol Pharmacol. 1993 Jan;43(1):11-6. Mol Pharmacol. 1993. PMID: 7678690

2

Biochemical characterization of HIV-1 reverse transcriptases encoding mutations at amino acid residues 161 and 208 involved in resistance to phosphonoformate.

Tramontano E, Piras G, Mellors JW, Putzolu M, Bazmi HZ, La Colla P. Tramontano E, et al. Among authors: piras g. Biochem Pharmacol. 1998 Dec 15;56(12):1583-9. doi: 10.1016/s0006-2952(98)00206-8. Biochem Pharmacol. 1998. PMID: 9973178

3

Action of uracil analogs on human immunodeficiency virus type 1 and its reverse transcriptase.

Piras G, Dutschman GE, Im GJ, Pan BC, Chu SH, Cheng YC. Piras G, et al. Antimicrob Agents Chemother. 1995 Feb;39(2):539-41. doi: 10.1128/AAC.39.2.539. Antimicrob Agents Chemother. 1995. PMID: 7537030 Free PMC article.

4

Amino acid substitutions in HIV-1 reverse transcriptase with corresponding residues from HIV-2. Effect on kinetic constants and inhibition by non-nucleoside analogs.

Bacolla A, Shih CK, Rose JM, Piras G, Warren TC, Grygon CA, Ingraham RH, Cousins RC, Greenwood DJ, Richman D, et al. Bacolla A, et al. Among authors: piras g. J Biol Chem. 1993 Aug 5;268(22):16571-7. J Biol Chem. 1993. PMID: 7688367 Free article.

5

2-Sulfonyl-4-chloroanilino moiety: a potent pharmacophore for the anti-human immunodeficiency virus type 1 activity of pyrrolyl aryl sulfones.

Artico M, Silvestri R, Massa S, Loi AG, Corrias S, Piras G, La Colla P. Artico M, et al. Among authors: piras g. J Med Chem. 1996 Jan 19;39(2):522-30. doi: 10.1021/jm950568w. J Med Chem. 1996. PMID: 8558522

6

Synthesis and antiviral activity of 8-aza analogs of chiral [2-(phosphonomethoxy) propyl]guanines.

Franchetti P, Sheikha GA, Cappellacci L, Grifantini M, De Montis A, Piras G, Loi AG, La Colla P. Franchetti P, et al. Among authors: piras g. J Med Chem. 1995 Sep 29;38(20):4007-13. doi: 10.1021/jm00020a015. J Med Chem. 1995. PMID: 7562935

7

4-Diazo-5-alkylsulphonamidopyrazoles: synthesis and evaluation of biological activity.

Vicentini CB, Veronese AC, Giori P, Pani A, Piras G, Gabrielsen A, La Colla P. Vicentini CB, et al. Among authors: piras g. Farmaco. 1991 Nov;46(11):1351-63. Farmaco. 1991. PMID: 1811620

8

DNA demethylation reactivates a subset of imprinted genes in uniparental mouse embryonic fibroblasts.

El Kharroubi A, Piras G, Stewart CL. El Kharroubi A, et al. Among authors: piras g. J Biol Chem. 2001 Mar 23;276(12):8674-80. doi: 10.1074/jbc.M009392200. Epub 2000 Dec 21. J Biol Chem. 2001. PMID: 11124954 Free article.

9

Human T-cell leukemia virus type I Tax protein transactivates RNA polymerase III promoter in vitro and in vivo.

Piras G, Dittmer J, Radonovich MF, Brady JN. Piras G, et al. J Biol Chem. 1996 Aug 23;271(34):20501-6. doi: 10.1074/jbc.271.34.20501. J Biol Chem. 1996. PMID: 8702791 Free article.

10

Three-drug combination of MKC-442, lamivudine and zidovudine in vitro: potential approach towards effective chemotherapy against HIV-1.

Piras G, Nakade K, Yuasa S, Baba M. Piras G, et al. AIDS. 1997 Mar 15;11(4):469-75. doi: 10.1097/00002030-199704000-00010. AIDS. 1997. PMID: 9084794

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