Kuromitsu S - Search Results

1

Soluble human high-affinity receptor for IgE abrogates the IgE-mediated allergic reaction.

Ra C, Kuromitsu S, Hirose T, Yasuda S, Furuichi K, Okumura K. Ra C, et al. Among authors: kuromitsu s. Int Immunol. 1993 Jan;5(1):47-54. doi: 10.1093/intimm/5.1.47. Int Immunol. 1993. PMID: 7680227

2

YM-341619 suppresses the differentiation of spleen T cells into Th2 cells in vitro, eosinophilia, and airway hyperresponsiveness in rat allergic models.

Ohga K, Kuromitsu S, Takezawa R, Numazaki M, Ishikawa J, Nagashima S, Shimizu Y. Ohga K, et al. Among authors: kuromitsu s. Eur J Pharmacol. 2008 Aug 20;590(1-3):409-16. doi: 10.1016/j.ejphar.2008.06.035. Epub 2008 Jun 14. Eur J Pharmacol. 2008. PMID: 18590722

3

Novel 7H-pyrrolo[2,3-d]pyrimidine derivatives as potent and orally active STAT6 inhibitors.

Nagashima S, Hondo T, Nagata H, Ogiyama T, Maeda J, Hoshii H, Kontani T, Kuromitsu S, Ohga K, Orita M, Ohno K, Moritomo A, Shiozuka K, Furutani M, Takeuchi M, Ohta M, Tsukamoto S. Nagashima S, et al. Among authors: kuromitsu s. Bioorg Med Chem. 2009 Oct 1;17(19):6926-36. doi: 10.1016/j.bmc.2009.08.021. Epub 2009 Aug 15. Bioorg Med Chem. 2009. PMID: 19747833

4

Synthesis and evaluation of 2-{[2-(4-hydroxyphenyl)-ethyl]amino}pyrimidine-5-carboxamide derivatives as novel STAT6 inhibitors.

Nagashima S, Yokota M, Nakai E, Kuromitsu S, Ohga K, Takeuchi M, Tsukamoto S, Ohta M. Nagashima S, et al. Among authors: kuromitsu s. Bioorg Med Chem. 2007 Jan 15;15(2):1044-55. doi: 10.1016/j.bmc.2006.10.015. Epub 2006 Oct 27. Bioorg Med Chem. 2007. PMID: 17071093

5

Identification of 4-benzylamino-2-[(4-morpholin-4-ylphenyl)amino]pyrimidine-5-carboxamide derivatives as potent and orally bioavailable STAT6 inhibitors.

Nagashima S, Nagata H, Iwata M, Yokota M, Moritomo H, Orita M, Kuromitsu S, Koakutsu A, Ohga K, Takeuchi M, Ohta M, Tsukamoto S. Nagashima S, et al. Among authors: kuromitsu s. Bioorg Med Chem. 2008 Jul 1;16(13):6509-21. doi: 10.1016/j.bmc.2008.05.031. Epub 2008 May 17. Bioorg Med Chem. 2008. PMID: 18534856

6

3-(13-Hydroxytridecyl)-1-[13-(3-pyridyl)tridecyl]pyridinium chloride (YM-53792), a novel inhibitor of NF-AT activation.

Kuromitsu S, Fukunaga M, Lennard AC, Masuho Y, Nakada S. Kuromitsu S, et al. Biochem Pharmacol. 1997 Nov 1;54(9):999-1005. doi: 10.1016/s0006-2952(97)00289-x. Biochem Pharmacol. 1997. PMID: 9374420

7

YM-201627: an orally active antitumor agent with selective inhibition of vascular endothelial cell proliferation.

Amino N, Ideyama Y, Yamano M, Kuromitsu S, Tajinda K, Samizu K, Matsuhisa A, Kudoh M, Shibasaki M. Amino N, et al. Among authors: kuromitsu s. Cancer Lett. 2006 Jul 8;238(1):119-27. doi: 10.1016/j.canlet.2005.06.037. Epub 2005 Aug 10. Cancer Lett. 2006. PMID: 16095812

8

YM-231146, a novel orally bioavailable inhibitor of vascular endothelial growth factor receptor-2, is effective against paclitaxel resistant tumors.

Amino N, Ideyama Y, Yamano M, Kuromitsu S, Tajinda K, Samizu K, Matsuhisa A, Shirasuna K, Kudoh M, Shibasaki M. Amino N, et al. Among authors: kuromitsu s. Biol Pharm Bull. 2005 Nov;28(11):2096-101. doi: 10.1248/bpb.28.2096. Biol Pharm Bull. 2005. PMID: 16272696 Free article.

9

YM-359445, an orally bioavailable vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor, has highly potent antitumor activity against established tumors.

Amino N, Ideyama Y, Yamano M, Kuromitsu S, Tajinda K, Samizu K, Hisamichi H, Matsuhisa A, Shirasuna K, Kudoh M, Shibasaki M. Amino N, et al. Among authors: kuromitsu s. Clin Cancer Res. 2006 Mar 1;12(5):1630-8. doi: 10.1158/1078-0432.CCR-05-2028. Clin Cancer Res. 2006. PMID: 16533791

10

The selective anaplastic lymphoma receptor tyrosine kinase inhibitor ASP3026 induces tumor regression and prolongs survival in non-small cell lung cancer model mice.

Mori M, Ueno Y, Konagai S, Fushiki H, Shimada I, Kondoh Y, Saito R, Mori K, Shindou N, Soga T, Sakagami H, Furutani T, Doihara H, Kudoh M, Kuromitsu S. Mori M, et al. Among authors: kuromitsu s. Mol Cancer Ther. 2014 Feb;13(2):329-40. doi: 10.1158/1535-7163.MCT-13-0395. Epub 2014 Jan 13. Mol Cancer Ther. 2014. PMID: 24419060

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