Lin CM - Search Results

1

Synthesis, antitubulin and antimitotic activity, and cytotoxicity of analogs of 2-methoxyestradiol, an endogenous mammalian metabolite of estradiol that inhibits tubulin polymerization by binding to the colchicine binding site.

Cushman M, He HM, Katzenellenbogen JA, Lin CM, Hamel E. Cushman M, et al. Among authors: lin cm. J Med Chem. 1995 Jun 9;38(12):2041-9. doi: 10.1021/jm00012a003. J Med Chem. 1995. PMID: 7783135

2

Synthesis and evaluation of analogues of (Z)-1-(4-methoxyphenyl)-2-(3,4,5-trimethoxyphenyl)ethene as potential cytotoxic and antimitotic agents.

Cushman M, Nagarathnam D, Gopal D, He HM, Lin CM, Hamel E. Cushman M, et al. Among authors: lin cm. J Med Chem. 1992 Jun 12;35(12):2293-306. doi: 10.1021/jm00090a021. J Med Chem. 1992. PMID: 1613753

3

Synthesis and evaluation of stilbene and dihydrostilbene derivatives as potential anticancer agents that inhibit tubulin polymerization.

Cushman M, Nagarathnam D, Gopal D, Chakraborti AK, Lin CM, Hamel E. Cushman M, et al. Among authors: lin cm. J Med Chem. 1991 Aug;34(8):2579-88. doi: 10.1021/jm00112a036. J Med Chem. 1991. PMID: 1875350

4

Antitubulin effects of derivatives of 3-demethylthiocolchicine, methylthio ethers of natural colchicinoids, and thioketones derived from thiocolchicine. Comparison with colchicinoids.

Muzaffar A, Brossi A, Lin CM, Hamel E. Muzaffar A, et al. Among authors: lin cm. J Med Chem. 1990 Feb;33(2):567-71. doi: 10.1021/jm00164a015. J Med Chem. 1990. PMID: 2299625

5

Antitumor agents. 150. 2',3',4',5',5,6,7-substituted 2-phenyl-4-quinolones and related compounds: their synthesis, cytotoxicity, and inhibition of tubulin polymerization.

Li L, Wang HK, Kuo SC, Wu TS, Lednicer D, Lin CM, Hamel E, Lee KH. Li L, et al. Among authors: lin cm. J Med Chem. 1994 Apr 15;37(8):1126-35. doi: 10.1021/jm00034a010. J Med Chem. 1994. PMID: 8164254

6

Synthesis and cytotoxicity of 1,6,7,8-substituted 2-(4'-substituted phenyl)-4-quinolones and related compounds: identification as antimitotic agents interacting with tubulin.

Kuo SC, Lee HZ, Juang JP, Lin YT, Wu TS, Chang JJ, Lednicer D, Paull KD, Lin CM, Hamel E, et al. Kuo SC, et al. Among authors: lin cm, lin yt. J Med Chem. 1993 Apr 30;36(9):1146-56. doi: 10.1021/jm00061a005. J Med Chem. 1993. PMID: 8387598

7

Synthesis and evaluation of a series of benzylaniline hydrochlorides as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization.

Cushman M, He HM, Lin CM, Hamel E. Cushman M, et al. Among authors: lin cm. J Med Chem. 1993 Sep 17;36(19):2817-21. doi: 10.1021/jm00071a012. J Med Chem. 1993. PMID: 8410995

8

Antitumor agents. 141. Synthesis and biological evaluation of novel thiocolchicine analogs: N-acyl-, N-aroyl-, and N-(substituted benzyl)deacetylthiocolchicines as potent cytotoxic and antimitotic compounds.

Sun L, Hamel E, Lin CM, Hastie SB, Pyluck A, Lee KH. Sun L, et al. Among authors: lin cm. J Med Chem. 1993 May 14;36(10):1474-9. doi: 10.1021/jm00062a021. J Med Chem. 1993. PMID: 8496915

9

Antitumor agents. 139. Synthesis and biological evaluation of thiocolchicine analogs 5,6-dihydro-6(S)-(acyloxy)- and 5,6-dihydro-6(S)-[(aroyloxy)methyl]-1,2,3-trimethoxy-9-(methylthio)-8H- cyclohepta[a]naphthalen-8-ones as novel cytotoxic and antimitotic agents.

Sun L, McPhail AT, Hamel E, Lin CM, Hastie SB, Chang JJ, Lee KH. Sun L, et al. Among authors: lin cm. J Med Chem. 1993 Mar 5;36(5):544-51. doi: 10.1021/jm00057a004. J Med Chem. 1993. PMID: 8496935

10

Synthesis and biological activity of A-nor-paclitaxel analogues.

Chordia MD, Kingston DG, Hamel E, Lin CM, Long BH, Fairchild CA, Johnston KA, Rose WC. Chordia MD, et al. Among authors: lin cm. Bioorg Med Chem. 1997 May;5(5):941-7. doi: 10.1016/s0968-0896(97)00035-7. Bioorg Med Chem. 1997. PMID: 9208103

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