Legrum W - Search Results

1

Liposomes as a tool in experimental pharmacology and toxicology.

Tegtmeier M, Wölfel K, Sommerlad C, Legrum W. Tegtmeier M, et al. Among authors: legrum w. Pharmazie. 1995 Jan;50(1):73-4. Pharmazie. 1995. PMID: 7886132 No abstract available.

2

7-Aminocoumarins are substrates of cytochrome P450-isozymes.

Tegtmeier M, Legrum W. Tegtmeier M, et al. Among authors: legrum w. Arch Pharm (Weinheim). 1998 Apr;331(4):143-8. doi: 10.1002/(sici)1521-4184(199804)331:4<143::aid-ardp143>3.0.co;2-d. Arch Pharm (Weinheim). 1998. PMID: 9648523

3

Selective inducers of the Coh-locus enhance the metabolisms of coumarin- and of quinoline-derivatives but not that of naphthalenes.

Netter KJ, Hahnemann B, Mangoura SA, Feil F, Tegtmeier M, Mayer RT, Legrum W. Netter KJ, et al. Among authors: legrum w. Adv Exp Med Biol. 1991;283:353-7. doi: 10.1007/978-1-4684-5877-0_46. Adv Exp Med Biol. 1991. PMID: 2069007 No abstract available.

4

Approach to detect substrates suitable to measure the coumarin 7-hydroxylase (Cyp 2a-5)-structure-activity relationships.

Tegtmeier M, Legrum W. Tegtmeier M, et al. Among authors: legrum w. Arch Pharm (Weinheim). 1994 May;327(5):299-302. doi: 10.1002/ardp.19943270506. Arch Pharm (Weinheim). 1994. PMID: 8010881

5

Inorganic tin -- a new selective inducer of the murine coumarin 7-hydroxylase (CYP2A5).

Emde B, Tegtmeier M, Hahnemann B, Legrum W. Emde B, et al. Among authors: legrum w. Toxicology. 1996 Apr 15;108(1-2):73-8. doi: 10.1016/0300-483x(95)03285-n. Toxicology. 1996. PMID: 8644120

6

Metabolic and analytical interactions of grapefruit juice and 1,2-benzopyrone (coumarin) in man.

Runkel M, Tegtmeier M, Legrum W. Runkel M, et al. Among authors: legrum w. Eur J Clin Pharmacol. 1996;50(3):225-30. doi: 10.1007/s002280050097. Eur J Clin Pharmacol. 1996. PMID: 8737764

7

The character of inhibition of the metabolism of 1,2-benzopyrone (coumarin) by grapefruit juice in human.

Runkel M, Bourian M, Tegtmeier M, Legrum W. Runkel M, et al. Among authors: legrum w. Eur J Clin Pharmacol. 1997;53(3-4):265-9. doi: 10.1007/s002280050374. Eur J Clin Pharmacol. 1997. PMID: 9476043

8

A new method of capillary electrophoresis for metabolites of coumarin.

Tegtmeier M, Mühlau A, Dücker D, Runkel M, Legrum W. Tegtmeier M, et al. Among authors: legrum w. Pharmazie. 2000 Feb;55(2):94-6. Pharmazie. 2000. PMID: 10723765

9

Naringenin and interindividual variability in interaction of coumarin with grapefruit juice.

Bourian M, Runkel M, Krisp A, Tegtmeier M, Freudenstein J, Legrum W. Bourian M, et al. Among authors: legrum w. Exp Toxicol Pathol. 1999 Jul;51(4-5):289-93. doi: 10.1016/S0940-2993(99)80008-6. Exp Toxicol Pathol. 1999. PMID: 10445384 Clinical Trial.

10

Single copy of variant CYP2A6 alleles does not confer susceptibility to liver dysfunction in patients treated with coumarin.

Burian M, Freudenstein J, Tegtmeier M, Naser-Hijazi B, Henneicke-von Zepelin HH, Legrum W. Burian M, et al. Among authors: legrum w. Int J Clin Pharmacol Ther. 2003 Apr;41(4):141-7. doi: 10.5414/cpp41141. Int J Clin Pharmacol Ther. 2003. PMID: 12708602 Clinical Trial.

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