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Structure-activity relationships for a novel series of pyrido[2,3-d]pyrimidine tyrosine kinase inhibitors.
Hamby JM, Connolly CJ, Schroeder MC, Winters RT, Showalter HD, Panek RL, Major TC, Olsewski B, Ryan MJ, Dahring T, Lu GH, Keiser J, Amar A, Shen C, Kraker AJ, Slintak V, Nelson JM, Fry DW, Bradford L, Hallak H, Doherty AM. Hamby JM, et al. Among authors: ryan mj. J Med Chem. 1997 Jul 18;40(15):2296-303. doi: 10.1021/jm970367n. J Med Chem. 1997. PMID: 9240345
Animal model that mimics atherosclerotic plaque rupture.
Rekhter MD, Hicks GW, Brammer DW, Work CW, Kim JS, Gordon D, Keiser JA, Ryan MJ. Rekhter MD, et al. Among authors: ryan mj. Circ Res. 1998 Oct 5;83(7):705-13. doi: 10.1161/01.res.83.7.705. Circ Res. 1998. PMID: 9758640
625 results