Pawson T - Search Results

1

Overexpression of Shc proteins potentiates the proliferative response to the granulocyte-macrophage colony-stimulating factor and recruitment of Grb2/SoS and Grb2/p140 complexes to the beta receptor subunit.

Lanfrancone L, Pelicci G, Brizzi MF, Aronica MG, Casciari C, Giuli S, Pegoraro L, Pawson T, Pelicci PG, Arouica MG. Lanfrancone L, et al. Among authors: pawson t. Oncogene. 1995 Mar 2;10(5):907-17. Oncogene. 1995. PMID: 7898932

2

Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins.

Salcini AE, McGlade J, Pelicci G, Nicoletti I, Pawson T, Pelicci PG. Salcini AE, et al. Among authors: pawson t. Oncogene. 1994 Oct;9(10):2827-36. Oncogene. 1994. PMID: 8084588

3

Shc products are substrates of erbB-2 kinase.

Segatto O, Pelicci G, Giuli S, Digiesi G, Di Fiore PP, McGlade J, Pawson T, Pelicci PG. Segatto O, et al. Among authors: pawson t. Oncogene. 1993 Aug;8(8):2105-12. Oncogene. 1993. PMID: 8101647

4

Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway.

Migliaccio E, Mele S, Salcini AE, Pelicci G, Lai KM, Superti-Furga G, Pawson T, Di Fiore PP, Lanfrancone L, Pelicci PG. Migliaccio E, et al. Among authors: pawson t. EMBO J. 1997 Feb 17;16(4):706-16. doi: 10.1093/emboj/16.4.706. EMBO J. 1997. PMID: 9049300 Free PMC article.

5

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction.

Pelicci G, Lanfrancone L, Grignani F, McGlade J, Cavallo F, Forni G, Nicoletti I, Grignani F, Pawson T, Pelicci PG. Pelicci G, et al. Among authors: pawson t. Cell. 1992 Jul 10;70(1):93-104. doi: 10.1016/0092-8674(92)90536-l. Cell. 1992. PMID: 1623525

6

Shc proteins are phosphorylated and regulated by the v-Src and v-Fps protein-tyrosine kinases.

McGlade J, Cheng A, Pelicci G, Pelicci PG, Pawson T. McGlade J, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 1992 Oct 1;89(19):8869-73. doi: 10.1073/pnas.89.19.8869. Proc Natl Acad Sci U S A. 1992. PMID: 1409579 Free PMC article.

7

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases.

Rozakis-Adcock M, McGlade J, Mbamalu G, Pelicci G, Daly R, Li W, Batzer A, Thomas S, Brugge J, Pelicci PG, Schlessinger J, Pawson T, et al. Rozakis-Adcock M, et al. Among authors: pawson t. Nature. 1992 Dec 17;360(6405):689-92. doi: 10.1038/360689a0. Nature. 1992. PMID: 1465135

8

Insulin-induced phosphorylation of the 46- and 52-kDa Shc proteins.

Pronk GJ, McGlade J, Pelicci G, Pawson T, Bos JL. Pronk GJ, et al. Among authors: pawson t. J Biol Chem. 1993 Mar 15;268(8):5748-53. J Biol Chem. 1993. PMID: 8449939 Free article.

9

Bcr-Abl oncoproteins bind directly to activators of the Ras signalling pathway.

Puil L, Liu J, Gish G, Mbamalu G, Bowtell D, Pelicci PG, Arlinghaus R, Pawson T. Puil L, et al. Among authors: pawson t. EMBO J. 1994 Feb 15;13(4):764-73. doi: 10.1002/j.1460-2075.1994.tb06319.x. EMBO J. 1994. PMID: 8112292 Free PMC article.

10

The Rai (Shc C) adaptor protein regulates the neuronal stress response and protects against cerebral ischemia.

Troglio F, Echart C, Gobbi A, Pawson T, Pelicci PG, De Simoni MG, Pelicci G. Troglio F, et al. Among authors: pawson t. Proc Natl Acad Sci U S A. 2004 Oct 26;101(43):15476-81. doi: 10.1073/pnas.0403283101. Epub 2004 Oct 19. Proc Natl Acad Sci U S A. 2004. PMID: 15494442 Free PMC article.

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