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N-substituted dibenzoxazepines as analgesic PGE2 antagonists.
Hallinan EA, Hagen TJ, Husa RK, Tsymbalov S, Rao SN, vanHoeck JP, Rafferty MF, Stapelfeld A, Savage MA, Reichman M. Hallinan EA, et al. Among authors: vanhoeck jp. J Med Chem. 1993 Oct 29;36(22):3293-9. doi: 10.1021/jm00074a010. J Med Chem. 1993. PMID: 7901416
Synthesis of a peroxime proliferator activated receptor (PPAR) alpha/gamma agonist via stereocontrolled Williamson ether synthesis and stereospecific SN2 reaction of S-2-chloro propionic acid with phenoxides.
Aikins JA, Haurez M, Rizzo JR, Van Hoeck JP, Brione W, Kestemont JP, Stevens C, Lemair X, Stephenson GA, Marlot E, Forst M, Houpis IN. Aikins JA, et al. J Org Chem. 2005 Jun 10;70(12):4695-705. doi: 10.1021/jo050268e. J Org Chem. 2005. PMID: 15932307