Vander Velde DG - Search Results

1

Structure-activity studies of antitumor taxanes: synthesis of novel C-13 side chain homologated taxol and taxotere analogs.

Jayasinghe LR, Datta A, Ali SM, Zygmunt J, Vander Velde DG, Georg GI. Jayasinghe LR, et al. Among authors: vander velde dg. J Med Chem. 1994 Sep 2;37(18):2981-4. doi: 10.1021/jm00044a020. J Med Chem. 1994. PMID: 7915328

2

The effect of the aromatic rings of taxol on biological activity and solution conformation: synthesis and evaluation of saturated taxol and taxotere analogues.

Boge TC, Himes RH, Vander Velde DG, Georg GI. Boge TC, et al. Among authors: vander velde dg. J Med Chem. 1994 Sep 30;37(20):3337-43. doi: 10.1021/jm00046a018. J Med Chem. 1994. PMID: 7932561

3

A one-step synthesis of a deuterated paclitaxel analogue: 10-deacetoxy-(10alpha-2H)paclitaxel.

Dutta D, Hadd H, Vander Velde DG, Georg GI. Dutta D, et al. Among authors: vander velde dg. Bioorg Med Chem Lett. 1999 Dec 6;9(23):3277-8. doi: 10.1016/s0960-894x(99)00609-5. Bioorg Med Chem Lett. 1999. PMID: 10612584

4

Novel d-seco paclitaxel analogues: synthesis, biological evaluation, and model testing.

Barboni L, Datta A, Dutta D, Georg GI, Vander Velde DG, Himes RH, Wang M, Snyder JP. Barboni L, et al. Among authors: vander velde dg. J Org Chem. 2001 May 18;66(10):3321-9. doi: 10.1021/jo0015467. J Org Chem. 2001. PMID: 11348113

5

Synthesis, Conformational Analysis, and Biological Evaluation of Heteroaromatic Taxanes.

Georg GI, Harriman GC, Hepperle M, Clowers JS, Vander Velde DG, Himes RH. Georg GI, et al. Among authors: vander velde dg. J Org Chem. 1996 Apr 19;61(8):2664-2676. doi: 10.1021/jo951961c. J Org Chem. 1996. PMID: 11667096

6

Synthetic studies with 13-deoxybaccatin III.

Ahn YM, Vander Velde DG, Georg GI. Ahn YM, et al. Among authors: vander velde dg. J Org Chem. 2002 Oct 4;67(20):7140-3. doi: 10.1021/jo011183q. J Org Chem. 2002. PMID: 12354012

7

Total synthesis and evaluation of C25-benzyloxyepothilone C for tubulin assembly and cytotoxicity against MCF-7 breast cancer cells.

Hutt OE, Reddy BS, Nair SK, Reiff EA, Henri JT, Greiner JF, Chiu TL, Vandervelde DG, Amin EA, Himes RH, Georg GI. Hutt OE, et al. Bioorg Med Chem Lett. 2008 Sep 1;18(17):4904-6. doi: 10.1016/j.bmcl.2008.07.024. Epub 2008 Jul 11. Bioorg Med Chem Lett. 2008. PMID: 18684624 Free PMC article.

8

Total synthesis and evaluation of 22-(3-azidobenzoyloxy)methyl epothilone C for photoaffinity labeling of beta-tubulin.

Hutt OE, Inagaki J, Reddy BS, Nair SK, Reiff EA, Henri JT, Greiner JF, VanderVelde DG, Chiu TL, Amin EA, Himes RH, Georg GI. Hutt OE, et al. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3293-6. doi: 10.1016/j.bmcl.2009.04.077. Epub 2009 Apr 22. Bioorg Med Chem Lett. 2009. PMID: 19428248 Free PMC article.

9

Total synthesis and evaluation of C26-hydroxyepothilone D derivatives for photoaffinity labeling of beta-tubulin.

Reiff EA, Nair SK, Henri JT, Greiner JF, Reddy BS, Chakrasali R, David SA, Chiu TL, Amin EA, Himes RH, Vander Velde DG, Georg GI. Reiff EA, et al. Among authors: vander velde dg. J Org Chem. 2010 Jan 1;75(1):86-94. doi: 10.1021/jo901752v. J Org Chem. 2010. PMID: 19954175 Free PMC article.

10

The oxetane conformational lock of paclitaxel: structural analysis of D-secopaclitaxel.

Boge TC, Hepperle M, Vander Velde DG, Gunn CW, Grunewald GL, Georg GI. Boge TC, et al. Among authors: vander velde dg. Bioorg Med Chem Lett. 1999 Oct 18;9(20):3041-6. doi: 10.1016/s0960-894x(99)00521-1. Bioorg Med Chem Lett. 1999. PMID: 10571172

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