Newell DR - Search Results

1

Probing the active site and mechanism of action of O6-methylguanine-DNA methyltransferase with substrate analogues (O6-substituted guanines).

Arris CE, Bleasdale C, Calvert AH, Curtin NJ, Dalby C, Golding BT, Griffin RJ, Lunn JM, Major GN, Newell DR. Arris CE, et al. Among authors: newell dr. Anticancer Drug Des. 1994 Oct;9(5):401-8. Anticancer Drug Des. 1994. PMID: 7945724 No abstract available.

2

Future directions with carboplatin: can therapeutic monitoring, high-dose administration, and hematologic support with growth factors expand the spectrum compared with cisplatin?

Calvert AH, Newell DR, Gore ME. Calvert AH, et al. Among authors: newell dr. Semin Oncol. 1992 Feb;19(1 Suppl 2):155-63. Semin Oncol. 1992. PMID: 1411627 Review.

3

In vivo and ex vivo magnetic resonance spectroscopy as applied to pharmacokinetic studies with anticancer agents: a review.

Newell DR, Maxwell RJ, Golding BT. Newell DR, et al. NMR Biomed. 1992 Sep-Oct;5(5):273-8. doi: 10.1002/nbm.1940050514. NMR Biomed. 1992. PMID: 1449968 Review.

4

Clinical pharmacokinetics of the anthrapyrazole CI-941: factors compromising the implementation of a pharmacokinetically guided dose escalation scheme.

Graham MA, Newell DR, Foster BJ, Gumbrell LA, Jenns KE, Calvert AH. Graham MA, et al. Among authors: newell dr. Cancer Res. 1992 Feb 1;52(3):603-9. Cancer Res. 1992. PMID: 1732048 Clinical Trial.

5

The biochemical pharmacology of the thymidylate synthase inhibitor, 2-desamino-2-methyl-N10-propargyl-5,8-dideazafolic acid (ICI 198583).

Jackman AL, Newell DR, Gibson W, Jodrell DI, Taylor GA, Bishop JA, Hughes LR, Calvert AH. Jackman AL, et al. Among authors: newell dr. Biochem Pharmacol. 1991 Oct 24;42(10):1885-95. doi: 10.1016/0006-2952(91)90586-t. Biochem Pharmacol. 1991. PMID: 1741766

6

The pharmacokinetics of the quinazoline antifolate ICI D 1694 in mice and rats.

Jodrell DI, Newell DR, Gibson W, Hughes LR, Calvert AH. Jodrell DI, et al. Among authors: newell dr. Cancer Chemother Pharmacol. 1991;28(5):331-8. doi: 10.1007/BF00685685. Cancer Chemother Pharmacol. 1991. PMID: 1914075

7

The renal effects of N10-propargyl-5,8-dideazafolic acid (CB3717) and a non-nephrotoxic analogue ICI D1694, in mice.

Jodrell DI, Newell DR, Morgan SE, Clinton S, Bensted JP, Hughes LR, Calvert AH. Jodrell DI, et al. Among authors: newell dr. Br J Cancer. 1991 Nov;64(5):833-8. doi: 10.1038/bjc.1991.409. Br J Cancer. 1991. PMID: 1931603 Free PMC article.

8

Development of an assay for the estimation of N10-propargyl-5,8-dideazafolic acid polyglutamates in tumor cells.

Sikora E, Newell DR, Jackman AL, Simmonds AJ, Jones TR, Calvert AH. Sikora E, et al. Among authors: newell dr. Anal Biochem. 1988 Aug 1;172(2):344-55. doi: 10.1016/0003-2697(88)90454-x. Anal Biochem. 1988. PMID: 2461114

9

Formation and retention and biological activity of N10-propargyl-5,8-dideazafolic acid (CB3717) polyglutamates in L1210 cells in vitro.

Sikora E, Jackman AL, Newell DR, Calvert AH. Sikora E, et al. Among authors: newell dr. Biochem Pharmacol. 1988 Nov 1;37(21):4047-54. doi: 10.1016/0006-2952(88)90094-9. Biochem Pharmacol. 1988. PMID: 2461200

10

Carboplatin and etoposide pharmacokinetics in patients with testicular teratoma.

Newell DR, Eeles RA, Gumbrell LA, Boxall FE, Horwich A, Calvert AH. Newell DR, et al. Cancer Chemother Pharmacol. 1989;23(6):367-72. doi: 10.1007/BF00435838. Cancer Chemother Pharmacol. 1989. PMID: 2469544

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