Waterfield MD - Search Results

1

Phosphatidylinositol-3-OH kinase as a direct target of Ras.

Rodriguez-Viciana P, Warne PH, Dhand R, Vanhaesebroeck B, Gout I, Fry MJ, Waterfield MD, Downward J. Rodriguez-Viciana P, et al. Among authors: waterfield md. Nature. 1994 Aug 18;370(6490):527-32. doi: 10.1038/370527a0. Nature. 1994. PMID: 8052307

2

Structure of an SH2 domain of the p85 alpha subunit of phosphatidylinositol-3-OH kinase.

Booker GW, Breeze AL, Downing AK, Panayotou G, Gout I, Waterfield MD, Campbell ID. Booker GW, et al. Among authors: waterfield md. Nature. 1992 Aug 20;358(6388):684-7. doi: 10.1038/358684a0. Nature. 1992. PMID: 1323062

3

Biochemical characterization of the free catalytic p110 alpha and the complexed heterodimeric p110 alpha.p85 alpha forms of the mammalian phosphatidylinositol 3-kinase.

Woscholski R, Dhand R, Fry MJ, Waterfield MD, Parker PJ. Woscholski R, et al. Among authors: waterfield md. J Biol Chem. 1994 Oct 7;269(40):25067-72. J Biol Chem. 1994. PMID: 7929193 Free article.

4

Structure and function of phosphatidylinositol 3-kinase: a potential second messenger system involved in growth control.

Fry MJ, Waterfield MD. Fry MJ, et al. Among authors: waterfield md. Philos Trans R Soc Lond B Biol Sci. 1993 Jun 29;340(1293):337-44. doi: 10.1098/rstb.1993.0076. Philos Trans R Soc Lond B Biol Sci. 1993. PMID: 8103937 Review.

5

PI 3-kinase: structural and functional analysis of intersubunit interactions.

Dhand R, Hara K, Hiles I, Bax B, Gout I, Panayotou G, Fry MJ, Yonezawa K, Kasuga M, Waterfield MD. Dhand R, et al. Among authors: waterfield md. EMBO J. 1994 Feb 1;13(3):511-21. doi: 10.1002/j.1460-2075.1994.tb06289.x. EMBO J. 1994. PMID: 8313896 Free PMC article.

6

Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation.

Rodriguez-Viciana P, Warne PH, Vanhaesebroeck B, Waterfield MD, Downward J. Rodriguez-Viciana P, et al. Among authors: waterfield md. EMBO J. 1996 May 15;15(10):2442-51. EMBO J. 1996. PMID: 8665852 Free PMC article.

7

Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras.

Rodriguez-Viciana P, Warne PH, Khwaja A, Marte BM, Pappin D, Das P, Waterfield MD, Ridley A, Downward J. Rodriguez-Viciana P, et al. Among authors: waterfield md. Cell. 1997 May 2;89(3):457-67. doi: 10.1016/s0092-8674(00)80226-3. Cell. 1997. PMID: 9150145 Free article.

8

Purification and characterization of a phosphatidylinositol 3-kinase complex from bovine brain by using phosphopeptide affinity columns.

Fry MJ, Panayotou G, Dhand R, Ruiz-Larrea F, Gout I, Nguyen O, Courtneidge SA, Waterfield MD. Fry MJ, et al. Among authors: waterfield md. Biochem J. 1992 Dec 1;288 ( Pt 2)(Pt 2):383-93. doi: 10.1042/bj2880383. Biochem J. 1992. PMID: 1281404 Free PMC article.

9

Interaction of the p85 subunit of PI 3-kinase and its N-terminal SH2 domain with a PDGF receptor phosphorylation site: structural features and analysis of conformational changes.

Panayotou G, Bax B, Gout I, Federwisch M, Wroblowski B, Dhand R, Fry MJ, Blundell TL, Wollmer A, Waterfield MD. Panayotou G, et al. Among authors: waterfield md. EMBO J. 1992 Dec;11(12):4261-72. doi: 10.1002/j.1460-2075.1992.tb05524.x. EMBO J. 1992. PMID: 1330535 Free PMC article.

10

Expression and characterization of the p85 subunit of the phosphatidylinositol 3-kinase complex and a related p85 beta protein by using the baculovirus expression system.

Gout I, Dhand R, Panayotou G, Fry MJ, Hiles I, Otsu M, Waterfield MD. Gout I, et al. Among authors: waterfield md. Biochem J. 1992 Dec 1;288 ( Pt 2)(Pt 2):395-405. doi: 10.1042/bj2880395. Biochem J. 1992. PMID: 1334406 Free PMC article.

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