Nagel AA - Search Results

1

Novel inhibitors of prolyl endopeptidase: effects of stereochemistry.

Kolosko N, Bakker AV, Faraci WS, Nagel AA. Kolosko N, et al. Among authors: nagel aa. Drug Des Discov. 1994 Jan;11(1):61-71. Drug Des Discov. 1994. PMID: 8068820

2

2-Amino-4-methylpyridine as a potent inhibitor of inducible NO synthase activity in vitro and in vivo.

Faraci WS, Nagel AA, Verdries KA, Vincent LA, Xu H, Nichols LE, Labasi JM, Salter ED, Pettipher ER. Faraci WS, et al. Among authors: nagel aa. Br J Pharmacol. 1996 Nov;119(6):1101-8. doi: 10.1111/j.1476-5381.1996.tb16010.x. Br J Pharmacol. 1996. PMID: 8937711 Free PMC article.

3

Novel benzisoxazole derivatives as potent and selective inhibitors of acetylcholinesterase.

Villalobos A, Blake JF, Biggers CK, Butler TW, Chapin DS, Chen YL, Ives JL, Jones SB, Liston DR, Nagel AA, et al. Villalobos A, et al. Among authors: nagel aa. J Med Chem. 1994 Aug 19;37(17):2721-34. doi: 10.1021/jm00043a012. J Med Chem. 1994. PMID: 8064800

4

Design and synthesis of 1-heteroaryl-3-(1-benzyl-4-piperidinyl)propan-1-one derivatives as potent, selective acetylcholinesterase inhibitors.

Nagel AA, Liston DR, Jung S, Mahar M, Vincent LA, Chapin D, Chen YL, Hubbard S, Ives JL, Jones SB, et al. Nagel AA, et al. J Med Chem. 1995 Mar 31;38(7):1084-9. doi: 10.1021/jm00007a005. J Med Chem. 1995. PMID: 7707311

5

5,7-dihydro-3-[2-[1-(phenylmethyl)-4-piperidinyl]ethyl]-6H- pyrrolo[3,2-f]-1,2-benzisoxazol-6-one: a potent and centrally-selective inhibitor of acetylcholinesterase with an improved margin of safety.

Villalobos A, Butler TW, Chapin DS, Chen YL, DeMattos SB, Ives JL, Jones SB, Liston DR, Nagel AA, Nason DM, et al. Villalobos A, et al. Among authors: nagel aa. J Med Chem. 1995 Jul 21;38(15):2802-8. doi: 10.1021/jm00015a002. J Med Chem. 1995. PMID: 7636841

6

Thiazole as a carbonyl bioisostere. A novel class of highly potent and selective 5-HT3 receptor antagonists.

Rosen T, Nagel AA, Rizzi JP, Ives JL, Daffeh JB, Ganong AH, Guarino K, Heym J, McLean S, Nowakowski JT, et al. Rosen T, et al. Among authors: nagel aa. J Med Chem. 1990 Oct;33(10):2715-20. doi: 10.1021/jm00172a006. J Med Chem. 1990. PMID: 2213824

7

Aromatic thiazole derivatives: structurally novel and selective serotonin-3 receptor antagonists.

Nagel AA, Rosen T, Rizzi J, Daffeh J, Guarino K, Nowakowski J, Vincent LA, Heym J, McLean S, Seeger T, et al. Nagel AA, et al. J Med Chem. 1990 Jan;33(1):13-6. doi: 10.1021/jm00163a003. J Med Chem. 1990. PMID: 2296012 No abstract available.

8

Synthesis, in vitro binding profile, and central nervous system penetrability of the highly potent 5-HT3 receptor antagonist [3H]-4-(2-methoxyphenyl)-2-[4(5)-methyl-5(4)-imidazolylmethyl]thiazole.

Rosen T, Seeger TF, McLean S, Nagel AA, Ives JL, Guarino KJ, Bryce D, Furman J, Roth RW, Chalabi PM, et al. Rosen T, et al. Among authors: nagel aa. J Med Chem. 1990 Nov;33(11):3020-3. doi: 10.1021/jm00173a017. J Med Chem. 1990. PMID: 2231600

9

Synthesis, in vitro and in vivo activity of novel 9-deoxo-9a-AZA-9a-homoerythromycin A derivatives; a new class of macrolide antibiotics, the azalides.

Bright GM, Nagel AA, Bordner J, Desai KA, Dibrino JN, Nowakowska J, Vincent L, Watrous RM, Sciavolino FC, English AR, et al. Bright GM, et al. Among authors: nagel aa. J Antibiot (Tokyo). 1988 Aug;41(8):1029-47. doi: 10.7164/antibiotics.41.1029. J Antibiot (Tokyo). 1988. PMID: 3139603 Free article.

10

1-Naphthylpiperazine derivatives as potential atypical antipsychotic agents.

Lowe JA 3rd, Seeger TF, Nagel AA, Howard HR, Seymour PA, Heym JH, Ewing FE, Newman ME, Schmidt AW, Furman JS, et al. Lowe JA 3rd, et al. Among authors: nagel aa. J Med Chem. 1991 Jun;34(6):1860-6. doi: 10.1021/jm00110a016. J Med Chem. 1991. PMID: 1676427

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