Waltham M - Search Results

1

Transfection with a cDNA encoding a Ser31 or Ser34 mutant human dihydrofolate reductase into Chinese hamster ovary and mouse marrow progenitor cells confers methotrexate resistance.

Banerjee D, Schweitzer BI, Volkenandt M, Li MX, Waltham M, Mineishi S, Zhao SC, Bertino JR. Banerjee D, et al. Among authors: waltham m. Gene. 1994 Feb 25;139(2):269-74. doi: 10.1016/0378-1119(94)90768-4. Gene. 1994. PMID: 8112617

2

Methotrexate resistance in an in vivo mouse tumor due to a non-active-site dihydrofolate reductase mutation.

Dicker AP, Waltham MC, Volkenandt M, Schweitzer BI, Otter GM, Schmid FA, Sirotnak FM, Bertino JR. Dicker AP, et al. Among authors: waltham mc. Proc Natl Acad Sci U S A. 1993 Dec 15;90(24):11797-801. doi: 10.1073/pnas.90.24.11797. Proc Natl Acad Sci U S A. 1993. PMID: 8265628 Free PMC article.

3

Variants of human dihydrofolate reductase with substitutions at leucine-22: effect on catalytic and inhibitor binding properties.

Ercikan-Abali EA, Waltham MC, Dicker AP, Schweitzer BI, Gritsman H, Banerjee D, Bertino JR. Ercikan-Abali EA, et al. Among authors: waltham mc. Mol Pharmacol. 1996 Mar;49(3):430-7. Mol Pharmacol. 1996. PMID: 8643082

4

Active site-directed double mutants of dihydrofolate reductase.

Ercikan-Abali EA, Mineishi S, Tong Y, Nakahara S, Waltham MC, Banerjee D, Chen W, Sadelain M, Bertino JR. Ercikan-Abali EA, et al. Among authors: waltham mc. Cancer Res. 1996 Sep 15;56(18):4142-5. Cancer Res. 1996. PMID: 8797582

5

Translational regulation of the synthesis of dihydrofolate reductase.

Ercikan E, Banerjee D, Waltham M, Schnieders B, Scotto KW, Bertino JR. Ercikan E, et al. Among authors: waltham m. Adv Exp Med Biol. 1993;338:537-40. doi: 10.1007/978-1-4615-2960-6_109. Adv Exp Med Biol. 1993. PMID: 8304175 No abstract available.

6

Mutations leading to antifolate resistance in Chinese hamster ovary cells after exposure to the alkylating agent ethylmethanesulfonate.

Fanin R, Banerjee D, Volkenandt M, Waltham M, Li WW, Dicker AP, Schweitzer BI, Bertino JR. Fanin R, et al. Among authors: waltham m. Mol Pharmacol. 1993 Jul;44(1):13-21. Mol Pharmacol. 1993. PMID: 8341268

7

Dihydrofolate reductase protein inhibits its own translation by binding to dihydrofolate reductase mRNA sequences within the coding region.

Ercikan-Abali EA, Banerjee D, Waltham MC, Skacel N, Scotto KW, Bertino JR. Ercikan-Abali EA, et al. Among authors: waltham mc. Biochemistry. 1997 Oct 7;36(40):12317-22. doi: 10.1021/bi971026e. Biochemistry. 1997. PMID: 9315871

8

Increased activity of gamma-glutamyl hydrolase in human sarcoma cell lines: a novel mechanism of intrinsic resistance to methotrexate (MTX).

Li WW, Waltham M, Tong W, Schweitzer BI, Bertino JR. Li WW, et al. Among authors: waltham m. Adv Exp Med Biol. 1993;338:635-8. doi: 10.1007/978-1-4615-2960-6_131. Adv Exp Med Biol. 1993. PMID: 7508171 No abstract available.

9

Acute monocytic leukemia: a myeloid leukemia subset that may be sensitive to methotrexate.

Göker E, Kheradpour A, Waltham M, Banerjee D, Tong WP, Elisseyeff Y, Bertino JR. Göker E, et al. Among authors: waltham m. Leukemia. 1995 Feb;9(2):274-6. Leukemia. 1995. PMID: 7532768

10

Effect of codon 22 mutations on substrate and inhibitor binding for human dihydrofolate reductase.

Ercikan E, Waltham M, Dicker A, Schweitzer B, Bertino JR. Ercikan E, et al. Among authors: waltham m. Adv Exp Med Biol. 1993;338:515-9. doi: 10.1007/978-1-4615-2960-6_104. Adv Exp Med Biol. 1993. PMID: 8304170 No abstract available.

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