Digard P - Search Results

1

A net +1 frameshift permits synthesis of thymidine kinase from a drug-resistant herpes simplex virus mutant.

Hwang CB, Horsburgh B, Pelosi E, Roberts S, Digard P, Coen DM. Hwang CB, et al. Among authors: digard p. Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5461-5. doi: 10.1073/pnas.91.12.5461. Proc Natl Acad Sci U S A. 1994. PMID: 8202508 Free PMC article.

2

Specific inhibition of herpes simplex virus DNA polymerase by helical peptides corresponding to the subunit interface.

Digard P, Williams KP, Hensley P, Brooks IS, Dahl CE, Coen DM. Digard P, et al. Proc Natl Acad Sci U S A. 1995 Feb 28;92(5):1456-60. doi: 10.1073/pnas.92.5.1456. Proc Natl Acad Sci U S A. 1995. PMID: 7878000 Free PMC article.

3

Unusual regulation of expression of the herpes simplex virus DNA polymerase gene.

Wobbe KK, Digard P, Staknis D, Coen DM. Wobbe KK, et al. Among authors: digard p. J Virol. 1993 Sep;67(9):5419-25. doi: 10.1128/JVI.67.9.5419-5425.1993. J Virol. 1993. PMID: 8394456 Free PMC article.

4

A novel functional domain of an alpha-like DNA polymerase. The binding site on the herpes simplex virus polymerase for the viral UL42 protein.

Digard P, Coen DM. Digard P, et al. J Biol Chem. 1990 Oct 15;265(29):17393-6. J Biol Chem. 1990. PMID: 2170378 Free article.

5

The extreme C terminus of herpes simplex virus DNA polymerase is crucial for functional interaction with processivity factor UL42 and for viral replication.

Digard P, Bebrin WR, Weisshart K, Coen DM. Digard P, et al. J Virol. 1993 Jan;67(1):398-406. doi: 10.1128/JVI.67.1.398-406.1993. J Virol. 1993. PMID: 8380085 Free PMC article.

6

Functional analysis of the herpes simplex virus UL42 protein.

Digard P, Chow CS, Pirrit L, Coen DM. Digard P, et al. J Virol. 1993 Mar;67(3):1159-68. doi: 10.1128/JVI.67.3.1159-1168.1993. J Virol. 1993. PMID: 8437207 Free PMC article.

7

Secondary structure and structure-activity relationships of peptides corresponding to the subunit interface of herpes simplex virus DNA polymerase.

Bridges KG, Hua Q, Brigham-Burke MR, Martin JD, Hensley P, Dahl CE, Digard P, Weiss MA, Coen DM. Bridges KG, et al. Among authors: digard p. J Biol Chem. 2000 Jan 7;275(1):472-8. doi: 10.1074/jbc.275.1.472. J Biol Chem. 2000. PMID: 10617641 Free article.

8

Polymerization activity of an alpha-like DNA polymerase requires a conserved 3'-5' exonuclease active site.

Gibbs JS, Weisshart K, Digard P, deBruynKops A, Knipe DM, Coen DM. Gibbs JS, et al. Among authors: digard p. Mol Cell Biol. 1991 Sep;11(9):4786-95. doi: 10.1128/mcb.11.9.4786-4795.1991. Mol Cell Biol. 1991. PMID: 1652064 Free PMC article.

9

Mutational analysis of DNA polymerase substrate recognition and subunit interactions using herpes simplex virus as prototype.

Digard P, Bebrin WR, Coen DM. Digard P, et al. Methods Enzymol. 1995;262:303-22. doi: 10.1016/0076-6879(95)62026-5. Methods Enzymol. 1995. PMID: 8594357 No abstract available.

10

Small molecule inhibitors of influenza A and B viruses that act by disrupting subunit interactions of the viral polymerase.

Muratore G, Goracci L, Mercorelli B, Foeglein Á, Digard P, Cruciani G, Palù G, Loregian A. Muratore G, et al. Among authors: digard p. Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6247-52. doi: 10.1073/pnas.1119817109. Epub 2012 Apr 2. Proc Natl Acad Sci U S A. 2012. PMID: 22474359 Free PMC article.

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