The 180-kDa isoform of topoisomerase II is localized in the nucleolus and belongs to the structural elements of the nucleolar remnant.
Zini N, Martelli AM, Sabatelli P, Santi S, Negri C, Astaldi Ricotti GC, Maraldi NM.
Zini N, et al. Among authors: negri c.
Exp Cell Res. 1992 Jun;200(2):460-6. doi: 10.1016/0014-4827(92)90196-f.
Exp Cell Res. 1992.
PMID: 1315289
Monoclonal antibodies raised against two isoforms (170 and 150/180 kDa) of DNA topoisomerase II showed distinct fluorescence patterns in HeLa cells in different moments of the cell cycle (C. Negri et al., 1992, Exp. Cell Res. 200, 452-459). The ultrastructural distr …
Monoclonal antibodies raised against two isoforms (170 and 150/180 kDa) of DNA topoisomerase II showed distinct fluorescence patterns in HeL …