Palmer JT - Search Results

1

The effects of fluoromethyl ketone inhibitors of cathepsin B on adjuvant induced arthritis.

Esser RE, Watts LM, Angelo RA, Thornburg LP, Prior JJ, Palmer JT. Esser RE, et al. Among authors: palmer jt. J Rheumatol. 1993 Jul;20(7):1176-83. J Rheumatol. 1993. PMID: 8371213

2

Cysteine proteinase inhibitors decrease articular cartilage and bone destruction in chronic inflammatory arthritis.

Esser RE, Angelo RA, Murphey MD, Watts LM, Thornburg LP, Palmer JT, Talhouk JW, Smith RE. Esser RE, et al. Among authors: palmer jt. Arthritis Rheum. 1994 Feb;37(2):236-47. doi: 10.1002/art.1780370213. Arthritis Rheum. 1994. PMID: 8129779

3

Peptidyl fluoromethyl ketones as inhibitors of cathepsin B. Implication for treatment of rheumatoid arthritis.

Ahmed NK, Martin LA, Watts LM, Palmer J, Thornburg L, Prior J, Esser RE. Ahmed NK, et al. Biochem Pharmacol. 1992 Sep 25;44(6):1201-7. doi: 10.1016/0006-2952(92)90385-v. Biochem Pharmacol. 1992. PMID: 1417942

4

Novel route to the synthesis of peptides containing 2-amino-1'-hydroxymethyl ketones and their application as cathepsin K inhibitors.

Mendonca RV, Venkatraman S, Palmer JT. Mendonca RV, et al. Among authors: palmer jt. Bioorg Med Chem Lett. 2002 Oct 21;12(20):2887-91. doi: 10.1016/s0960-894x(02)00611-x. Bioorg Med Chem Lett. 2002. PMID: 12270170

5

A novel class of nonpeptidic biaryl inhibitors of human cathepsin K.

Robichaud J, Oballa R, Prasit P, Falgueyret JP, Percival MD, Wesolowski G, Rodan SB, Kimmel D, Johnson C, Bryant C, Venkatraman S, Setti E, Mendonca R, Palmer JT. Robichaud J, et al. Among authors: palmer jt. J Med Chem. 2003 Aug 14;46(17):3709-27. doi: 10.1021/jm0301078. J Med Chem. 2003. PMID: 12904076

6

Trifluoroethylamines as amide isosteres in inhibitors of cathepsin K.

Black WC, Bayly CI, Davis DE, Desmarais S, Falgueyret JP, Léger S, Li CS, Massé F, McKay DJ, Palmer JT, Percival MD, Robichaud J, Tsou N, Zamboni R. Black WC, et al. Among authors: palmer jt. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4741-4. doi: 10.1016/j.bmcl.2005.07.071. Bioorg Med Chem Lett. 2005. PMID: 16154747

7

Cysteine protease activity is up-regulated in inflamed ankle joints of rats with adjuvant-induced arthritis and decreases with in vivo administration of a vinyl sulfone cysteine protease inhibitor.

Biroc SL, Gay S, Hummel K, Magill C, Palmer JT, Spencer DR, Sa S, Klaus JL, Michel BA, Rasnick D, Gay RE. Biroc SL, et al. Among authors: palmer jt. Arthritis Rheum. 2001 Mar;44(3):703-11. doi: 10.1002/1529-0131(200103)44:3<703::AID-ANR120>3.0.CO;2-2. Arthritis Rheum. 2001. PMID: 11263786 Free article.

8

pH Dependence of inhibitors targeting the occluding loop of cathepsin B.

Cathers BE, Barrett C, Palmer JT, Rydzewski RM. Cathers BE, et al. Among authors: palmer jt. Bioorg Chem. 2002 Aug;30(4):264-75. doi: 10.1016/s0045-2068(02)00009-3. Bioorg Chem. 2002. PMID: 12392705

9

Localization of rat cathepsin K in osteoclasts and resorption pits: inhibition of bone resorption and cathepsin K-activity by peptidyl vinyl sulfones.

Xia L, Kilb J, Wex H, Li Z, Lipyansky A, Breuil V, Stein L, Palmer JT, Dempster DW, Brömme D. Xia L, et al. Among authors: palmer jt. Biol Chem. 1999 Jun;380(6):679-87. doi: 10.1515/BC.1999.084. Biol Chem. 1999. PMID: 10430032

10

Keto-1,3,4-oxadiazoles as cathepsin K inhibitors.

Palmer JT, Hirschbein BL, Cheung H, McCarter J, Janc JW, Yu ZW, Wesolowski G. Palmer JT, et al. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2909-14. doi: 10.1016/j.bmcl.2006.03.001. Epub 2006 Mar 20. Bioorg Med Chem Lett. 2006. PMID: 16546382

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