Bock MG - Search Results

1

Development and pharmacological assessment of novel peptide and nonpeptide oxytocin antagonists.

Pettibone DJ, Clineschmidt BV, Bock MG, Evans BE, Freidinger RM, Veber DF, Williams PD. Pettibone DJ, et al. Among authors: bock mg. Regul Pept. 1993 Apr 29;45(1-2):289-93. doi: 10.1016/0167-0115(93)90222-t. Regul Pept. 1993. PMID: 8511358 Review. No abstract available.

2

Bradykinin agonist activity of a novel, potent oxytocin antagonist.

Pettibone DJ, Clineschmidt BV, Lis EV, Ransom RW, Totaro JA, Young GS, Bock MG, Freidinger RM, Veber DF, Williams PD. Pettibone DJ, et al. Among authors: bock mg. Eur J Pharmacol. 1991 Apr 24;196(3):233-7. doi: 10.1016/0014-2999(91)90435-s. Eur J Pharmacol. 1991. PMID: 1893911

3

In vitro pharmacological profile of a novel structural class of oxytocin antagonists.

Pettibone DJ, Clineschmidt BV, Lis EV, Reiss DR, Totaro JA, Woyden CJ, Bock MG, Freidinger RM, Tung RD, Veber DF, et al. Pettibone DJ, et al. Among authors: bock mg. J Pharmacol Exp Ther. 1991 Jan;256(1):304-8. J Pharmacol Exp Ther. 1991. PMID: 1988661

4

Antagonism of oxytocin in rats and pregnant rhesus monkeys by the novel cyclic hexapeptides, L-366,682 and L-366,948.

Clineschmidt BV, Pettibone DJ, Reiss DR, Lis EV, Haluska GJ, Novy MJ, Cook MJ, Cukierski MA, Kaufman MJ, Bock MG, et al. Clineschmidt BV, et al. Among authors: bock mg. J Pharmacol Exp Ther. 1991 Mar;256(3):827-32. J Pharmacol Exp Ther. 1991. PMID: 2005582

5

Cyclic hexapeptide oxytocin antagonists. Potency-, selectivity-, and solubility-enhancing modifications.

Freidinger RM, Williams PD, Tung RD, Bock MG, Pettibone DJ, Clineschmidt BV, DiPardo RM, Erb JM, Garsky VM, Gould NP, et al. Freidinger RM, et al. Among authors: bock mg. J Med Chem. 1990 Jul;33(7):1843-5. doi: 10.1021/jm00169a001. J Med Chem. 1990. PMID: 2163451 No abstract available.

6

1-((7,7-Dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl)butyramido)bicyclo [2.2.1]-heptan-1(S)-yl)methyl)sulfonyl)-4-(2-methylphenyl)piperaz ine (L-368,899): an orally bioavailable, non-peptide oxytocin antagonist with potential utility for managing preterm labor.

Williams PD, Anderson PS, Ball RG, Bock MG, Carroll L, Chiu SH, Clineschmidt BV, Culberson JC, Erb JM, Evans BE, et al. Williams PD, et al. Among authors: bock mg. J Med Chem. 1994 Mar 4;37(5):565-71. doi: 10.1021/jm00031a004. J Med Chem. 1994. PMID: 8126695

7

Progress in the development of oxytocin antagonists for use in preterm labor.

Pettibone DJ, Guidotti M, Harrell CM, Jasper JR, Lis EV, O'Brien JA, Reiss DR, Woyden CJ, Bock MG, Evans BE, et al. Pettibone DJ, et al. Among authors: bock mg. Adv Exp Med Biol. 1995;395:601-12. Adv Exp Med Biol. 1995. PMID: 8714024 Review.

8

Nonpeptide oxytocin antagonists: potent, orally bioavailable analogs of L-371,257 containing a 1-R-(pyridyl)ethyl ether terminus.

Kuo MS, Bock MG, Freidinger RM, Guidotti MT, Lis EV, Pawluczyk JM, Perlow DS, Pettibone DJ, Quigley AG, Reiss DR, Williams PD, Woyden CJ. Kuo MS, et al. Among authors: bock mg. Bioorg Med Chem Lett. 1998 Nov 3;8(21):3081-6. doi: 10.1016/S0960-894X(98)00568-X. Bioorg Med Chem Lett. 1998. PMID: 9873680

9

Progress in the development of oxytocin antagonists for use in preterm labor.

Williams PD, Bock MG, Evans BE, Freidinger RM, Pettibone DJ. Williams PD, et al. Among authors: bock mg. Adv Exp Med Biol. 1998;449:473-9. doi: 10.1007/978-1-4615-4871-3_61. Adv Exp Med Biol. 1998. PMID: 10026841

10

Nonpeptide oxytocin antagonists: analogs of L-371,257 with improved potency.

Williams PD, Bock MG, Evans BE, Freidinger RM, Gallicchio SN, Guidotti MT, Jacobson MA, Kuo MS, Levy MR, Lis EV, Michelson SR, Pawluczyk JM, Perlow DS, Pettibone DJ, Quigley AG, Reiss DR, Salvatore C, Stauffer KJ, Woyden CJ. Williams PD, et al. Among authors: bock mg. Bioorg Med Chem Lett. 1999 May 3;9(9):1311-6. doi: 10.1016/s0960-894x(99)00181-x. Bioorg Med Chem Lett. 1999. PMID: 10340620

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