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The relationship between CAG repeat length and age of onset differs for Huntington's disease patients with juvenile onset or adult onset.
Andresen JM, Gayán J, Djoussé L, Roberts S, Brocklebank D, Cherny SS; US-Venezuela Collaborative Research Group; HD MAPS Collaborative Research Group; Cardon LR, Gusella JF, MacDonald ME, Myers RH, Housman DE, Wexler NS. Andresen JM, et al. Among authors: wexler ns. Ann Hum Genet. 2007 May;71(Pt 3):295-301. doi: 10.1111/j.1469-1809.2006.00335.x. Epub 2006 Dec 19. Ann Hum Genet. 2007. PMID: 17181545
A genetic linkage map of the chromosome 4 short arm.
Locke PA, MacDonald ME, Srinidhi J, Gilliam TC, Tanzi RE, Conneally PM, Wexler NS, Haines JL, Gusella JF. Locke PA, et al. Among authors: wexler ns. Somat Cell Mol Genet. 1993 Jan;19(1):95-101. doi: 10.1007/BF01233958. Somat Cell Mol Genet. 1993. PMID: 8096345
Factors associated with HD CAG repeat instability in Huntington disease.
Wheeler VC, Persichetti F, McNeil SM, Mysore JS, Mysore SS, MacDonald ME, Myers RH, Gusella JF, Wexler NS; US-Venezuela Collaborative Research Group. Wheeler VC, et al. Among authors: wexler ns. J Med Genet. 2007 Nov;44(11):695-701. doi: 10.1136/jmg.2007.050930. Epub 2007 Jul 27. J Med Genet. 2007. PMID: 17660463 Free PMC article.
A molecular genetic approach to Huntington's disease.
Gusella JF, Wexler NS, Conneally PM. Gusella JF, et al. Among authors: wexler ns. Res Publ Assoc Res Nerv Ment Dis. 1987;65:133-41. Res Publ Assoc Res Nerv Ment Dis. 1987. PMID: 2968633 Review.
Population-specific genetic modification of Huntington's disease in Venezuela.
Chao MJ, Kim KH, Shin JW, Lucente D, Wheeler VC, Li H, Roach JC, Hood L, Wexler NS, Jardim LB, Holmans P, Jones L, Orth M, Kwak S, MacDonald ME, Gusella JF, Lee JM. Chao MJ, et al. Among authors: wexler ns. PLoS Genet. 2018 May 11;14(5):e1007274. doi: 10.1371/journal.pgen.1007274. eCollection 2018 May. PLoS Genet. 2018. PMID: 29750799 Free PMC article.
65 results