Connor DT - Search Results

1

Hydroxylamine analogs of 2,6-di-t-butylphenols: dual inhibitors of cyclooxygenase and 5-lipoxygenase or selective 5-lipoxygenase inhibitors.

Kramer JB, Capiris T, Sircar JC, Connor DT, Bornemeier DA, Dyer RD, Kuipers PJ, Kennedy JA, Wright CD, Okonkwo GC, et al. Kramer JB, et al. Among authors: connor dt. Bioorg Med Chem. 1995 Apr;3(4):403-10. doi: 10.1016/0968-0896(95)00027-e. Bioorg Med Chem. 1995. PMID: 8581424

2

Novel 1,2,4-oxadiazoles and 1,2,4-thiadiazoles as dual 5-lipoxygenase and cyclooxygenase inhibitors.

Unangst PC, Shrum GP, Connor DT, Dyer RD, Schrier DJ. Unangst PC, et al. Among authors: connor dt. J Med Chem. 1992 Oct 2;35(20):3691-8. doi: 10.1021/jm00098a015. J Med Chem. 1992. PMID: 1433181

3

Styrylpyrazoles, styrylisoxazoles, and styrylisothiazoles. Novel 5-lipoxygenase and cyclooxygenase inhibitors.

Flynn DL, Belliotti TR, Boctor AM, Connor DT, Kostlan CR, Nies DE, Ortwine DF, Schrier DJ, Sircar JC. Flynn DL, et al. Among authors: connor dt. J Med Chem. 1991 Feb;34(2):518-25. doi: 10.1021/jm00106a006. J Med Chem. 1991. PMID: 1847426

4

Nonsteroidal antiinflammatory drug hydroxamic acids. Dual inhibitors of both cyclooxygenase and 5-lipoxygenase.

Flynn DL, Capiris T, Cetenko WJ, Connor DT, Dyer RD, Kostlan CR, Nies DE, Schrier DJ, Sircar JC. Flynn DL, et al. Among authors: connor dt. J Med Chem. 1990 Aug;33(8):2070-2. doi: 10.1021/jm00170a004. J Med Chem. 1990. PMID: 2115586 No abstract available.

5

Inhibition of E-selectin-, ICAM-1-, and VCAM-1-mediated cell adhesion by benzo[b]thiophene-, benzofuran-, indole-, and naphthalene-2-carboxamides: identification of PD 144795 as an antiinflammatory agent.

Boschelli DH, Kramer JB, Khatana SS, Sorenson RJ, Connor DT, Ferin MA, Wright CD, Lesch ME, Imre K, Okonkwo GC, et al. Boschelli DH, et al. Among authors: connor dt. J Med Chem. 1995 Oct 27;38(22):4597-614. doi: 10.1021/jm00022a026. J Med Chem. 1995. PMID: 7473588

6

3-Alkoxybenzo[b]thiophene-2-carboxamides as inhibitors of neutrophil-endothelial cell adhesion.

Boschelli DH, Kramer JB, Connor DT, Lesch ME, Schrier DJ, Ferin MA, Wright CD. Boschelli DH, et al. Among authors: connor dt. J Med Chem. 1994 Mar 18;37(6):717-8. doi: 10.1021/jm00032a001. J Med Chem. 1994. PMID: 8145218 No abstract available.

7

Synthesis and biological evaluation of 5-[[3,5-bis(1,1-dimethylethyl)- 4-hydroxyphenyl]methylene]oxazoles, -thiazoles, and -imidazoles: novel dual 5-lipoxygenase and cyclooxygenase inhibitors with antiinflammatory activity.

Unangst PC, Connor DT, Cetenko WA, Sorenson RJ, Kostlan CR, Sircar JC, Wright CD, Schrier DJ, Dyer RD. Unangst PC, et al. Among authors: connor dt. J Med Chem. 1994 Jan 21;37(2):322-8. doi: 10.1021/jm00028a017. J Med Chem. 1994. PMID: 8295221

8

Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles as orally-active, nonulcerogenic antiinflammatory agents.

Mullican MD, Wilson MW, Connor DT, Kostlan CR, Schrier DJ, Dyer RD. Mullican MD, et al. Among authors: connor dt. J Med Chem. 1993 Apr 16;36(8):1090-9. doi: 10.1021/jm00060a017. J Med Chem. 1993. PMID: 8478906

9

1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities.

Boschelli DH, Connor DT, Bornemeier DA, Dyer RD, Kennedy JA, Kuipers PJ, Okonkwo GC, Schrier DJ, Wright CD. Boschelli DH, et al. Among authors: connor dt. J Med Chem. 1993 Jun 25;36(13):1802-10. doi: 10.1021/jm00065a002. J Med Chem. 1993. PMID: 8515419

10

Synthesis, structure-activity relationships, and in vivo evaluations of substituted di-tert-butylphenols as a novel class of potent, selective, and orally active cyclooxygenase-2 inhibitors. 1. Thiazolone and oxazolone series.

Song Y, Connor DT, Doubleday R, Sorenson RJ, Sercel AD, Unangst PC, Roth BD, Gilbertsen RB, Chan K, Schrier DJ, Guglietta A, Bornemeier DA, Dyer RD. Song Y, et al. Among authors: connor dt. J Med Chem. 1999 Apr 8;42(7):1151-60. doi: 10.1021/jm9805081. J Med Chem. 1999. PMID: 10197959

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