Walsh TF - Search Results

1

Pharmacology of L-744,453, a novel nonpeptidyl endothelin antagonist.

Williams DL Jr, Murphy KL, Nolan NA, O'Brien JA, Lis EV Jr, Pettibone DJ, Clineschmidt BV, Krause SM, Veber DF, Naylor EM, Chakravarty PK, Walsh TF, Dhanoa DM, Chen A, Bagley SW, Fitch KJ, Greenlee WJ. Williams DL Jr, et al. Among authors: walsh tf. Life Sci. 1996;58(14):1149-57. doi: 10.1016/0024-3205(96)00073-2. Life Sci. 1996. PMID: 8614266

2

Renal protection by a dual ETA/ETB endothelin antagonist, L-754,142, after aortic cross-clamping in the dog.

Krause SM, Walsh TF, Greenlee WJ, Ranaei R, Williams DL Jr, Kivlighn SD. Krause SM, et al. Among authors: walsh tf. J Am Soc Nephrol. 1997 Jul;8(7):1061-71. doi: 10.1681/ASN.V871061. J Am Soc Nephrol. 1997. PMID: 9219155

3

Characterization of endothelin receptors in the anesthetized ferret: a novel model for investigating the functional ET(B) receptor subtypes.

Krause SM, Nolan NA, Clayton FC, Walsh TF, Williams DL Jr. Krause SM, et al. Among authors: walsh tf. J Cardiovasc Pharmacol. 1999 Sep;34(3):359-67. doi: 10.1097/00005344-199909000-00007. J Cardiovasc Pharmacol. 1999. PMID: 10470993

4

Effects of L-749,329, an ET(A)/ET(B) endothelin receptor antagonist, in a porcine coronary artery injury model of vascular restenosis.

Huckle WR, Drag MD, Acker WR, Powers M, McFall RC, Holder DJ, Walsh TF, Schwartz RS, Greenlee WJ, Johnson RG Jr. Huckle WR, et al. Among authors: walsh tf. Circulation. 2001 Apr 10;103(14):1899-905. doi: 10.1161/01.cir.103.14.1899. Circulation. 2001. PMID: 11294810

5

A potent, nonpeptidyl 1H-quinolone antagonist for the gonadotropin-releasing hormone receptor.

DeVita RJ, Walsh TF, Young JR, Jiang J, Ujjainwalla F, Toupence RB, Parikh M, Huang SX, Fair JA, Goulet MT, Wyvratt MJ, Lo JL, Ren N, Yudkovitz JB, Yang YT, Cheng K, Cui J, Mount G, Rohrer SP, Schaeffer JM, Rhodes L, Drisko JE, McGowan E, MacIntyre DE, Vincent S, Carlin JR, Cameron J, Smith RG. DeVita RJ, et al. Among authors: walsh tf. J Med Chem. 2001 Mar 15;44(6):917-22. doi: 10.1021/jm000275p. J Med Chem. 2001. PMID: 11300873

6

Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides.

Walsh TF, Toupence RB, Young JR, Huang SX, Ujjainwalla F, DeVita RJ, Goulet MT, Wyvratt MJ Jr, Fisher MH, Lo JL, Ren N, Yudkovitz JB, Yang YT, Cheng K, Smith RG. Walsh TF, et al. Bioorg Med Chem Lett. 2000 Mar 6;10(5):443-7. doi: 10.1016/s0960-894x(00)00024-x. Bioorg Med Chem Lett. 2000. PMID: 10743944

7

Pharmacological evaluation of LH-21, a newly discovered molecule that binds to cannabinoid CB1 receptor.

Chen RZ, Frassetto A, Lao JZ, Huang RR, Xiao JC, Clements MJ, Walsh TF, Hale JJ, Wang J, Tong X, Fong TM. Chen RZ, et al. Among authors: walsh tf. Eur J Pharmacol. 2008 Apr 28;584(2-3):338-42. doi: 10.1016/j.ejphar.2008.02.029. Epub 2008 Feb 19. Eur J Pharmacol. 2008. PMID: 18336811

8

Design and syntheses of melanocortin subtype-4 receptor agonists. Part 2: discovery of the dihydropyridazinone motif.

Ujjainwalla F, Warner D, Snedden C, Grisson RD, Walsh TF, Wyvratt MJ, Kalyani RN, Macneil T, Tang R, Weinberg DH, Van der Ploeg L, Goulet MT. Ujjainwalla F, et al. Among authors: walsh tf. Bioorg Med Chem Lett. 2005 Sep 15;15(18):4023-8. doi: 10.1016/j.bmcl.2005.06.033. Bioorg Med Chem Lett. 2005. PMID: 16005624

9

Identification of Phe313 of the gonadotropin-releasing hormone (GnRH) receptor as a site critical for the binding of nonpeptide GnRH antagonists.

Cui J, Smith RG, Mount GR, Lo JL, Yu J, Walsh TF, Singh SB, DeVita RJ, Goulet MT, Schaeffer JM, Cheng K. Cui J, et al. Among authors: walsh tf. Mol Endocrinol. 2000 May;14(5):671-81. doi: 10.1210/mend.14.5.0464. Mol Endocrinol. 2000. PMID: 10809231

10

Synthesis and SAR of 5,6-diarylpyridines as human CB1 inverse agonists.

Meurer LC, Finke PE, Mills SG, Walsh TF, Toupence RB, Debenham JS, Goulet MT, Wang J, Tong X, Fong TM, Lao J, Schaeffer MT, Chen J, Shen CP, Sloan Stribling D, Shearman LP, Strack AM, Van der Ploeg LH. Meurer LC, et al. Among authors: walsh tf. Bioorg Med Chem Lett. 2005 Feb 1;15(3):645-51. doi: 10.1016/j.bmcl.2004.11.031. Bioorg Med Chem Lett. 2005. PMID: 15664830

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