Harrap KR - Search Results

1

Biotransformation of the platinum drug JM216 following oral administration to cancer patients.

Raynaud FI, Mistry P, Donaghue A, Poon GK, Kelland LR, Barnard CF, Murrer BA, Harrap KR. Raynaud FI, et al. Among authors: harrap kr. Cancer Chemother Pharmacol. 1996;38(2):155-62. doi: 10.1007/s002800050464. Cancer Chemother Pharmacol. 1996. PMID: 8616906

2

A novel trans-platinum coordination complex possessing in vitro and in vivo antitumor activity.

Kelland LR, Barnard CF, Mellish KJ, Jones M, Goddard PM, Valenti M, Bryant A, Murrer BA, Harrap KR. Kelland LR, et al. Among authors: harrap kr. Cancer Res. 1994 Nov 1;54(21):5618-22. Cancer Res. 1994. PMID: 7923207

3

Circumvention of acquired tetraplatin resistance in a human ovarian carcinoma cell line by a novel trans platinum complex, JM335 [trans ammine (cyclohexylamine) dichloro dihydroxo platinum (IV)].

Mellish KJ, Barnard CF, Kelland LR, Harrap KR. Mellish KJ, et al. Among authors: harrap kr. Int J Cancer. 1994 Oct 1;59(1):65-70. doi: 10.1002/ijc.2910590114. Int J Cancer. 1994. PMID: 7927906

4

Schedule dependency of orally administered bis-acetato-ammine-dichloro-cyclohexylamine-platinum(IV) (JM216) in vivo.

McKeage MJ, Kelland LR, Boxall FE, Valenti MR, Jones M, Goddard PM, Gwynne J, Harrap KR. McKeage MJ, et al. Among authors: harrap kr. Cancer Res. 1994 Aug 1;54(15):4118-22. Cancer Res. 1994. PMID: 8033145

5

Evaluation of novel ammine/amine platinum (IV) dicarboxylates in L1210 murine leukaemia cells sensitive and resistant to cisplatin, tetraplatin or carboplatin.

Orr RM, O'Neill CF, Nicolson MC, Barnard CF, Murrer BA, Giandomenico CM, Vollano JF, Harrap KR. Orr RM, et al. Among authors: harrap kr. Br J Cancer. 1994 Sep;70(3):415-20. doi: 10.1038/bjc.1994.320. Br J Cancer. 1994. PMID: 8080724 Free PMC article.

6

Preclinical toxicology and tissue platinum distribution of novel oral antitumour platinum complexes: ammine/amine platinum(IV) dicarboxylates.

McKeage MJ, Morgan SE, Boxall FE, Murrer BA, Hard GC, Harrap KR. McKeage MJ, et al. Among authors: harrap kr. Cancer Chemother Pharmacol. 1994;33(6):497-503. doi: 10.1007/BF00686508. Cancer Chemother Pharmacol. 1994. PMID: 8137461

7

Effect of buthionine sulfoximine on PtII and PtIV drug accumulation and the formation of glutathione conjugates in human ovarian-carcinoma cell lines.

Mistry P, Loh SY, Kelland LR, Harrap KR. Mistry P, et al. Among authors: harrap kr. Int J Cancer. 1993 Nov 11;55(5):848-56. doi: 10.1002/ijc.2910550526. Int J Cancer. 1993. PMID: 8244583

8

Mechanism of action of an orally administered platinum complex [ammine bis butyrato cyclohexylamine dichloroplatinum (IV) (JM221)] in intrinsically cisplatin-resistant human ovarian carcinoma in vitro.

McKeage MJ, Abel G, Kelland LR, Harrap KR. McKeage MJ, et al. Among authors: harrap kr. Br J Cancer. 1994 Jan;69(1):1-7. doi: 10.1038/bjc.1994.1. Br J Cancer. 1994. PMID: 8286188 Free PMC article.

9

In vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin.

Mellish KJ, Kelland LR, Harrap KR. Mellish KJ, et al. Among authors: harrap kr. Br J Cancer. 1993 Aug;68(2):240-50. doi: 10.1038/bjc.1993.322. Br J Cancer. 1993. PMID: 8347478 Free PMC article.

10

Preclinical antitumor evaluation of bis-acetato-ammine-dichloro-cyclohexylamine platinum(IV): an orally active platinum drug.

Kelland LR, Abel G, McKeage MJ, Jones M, Goddard PM, Valenti M, Murrer BA, Harrap KR. Kelland LR, et al. Among authors: harrap kr. Cancer Res. 1993 Jun 1;53(11):2581-6. Cancer Res. 1993. PMID: 8388318

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