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Page 1
Synthesis and pharmacological evaluation of new arylpiperazines. 3-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-quinazolidin-4-one - a dual serotonin 5-HT(1A)/5-HT(2A) receptor ligand with an anxiolytic-like activity.
Bojarski AJ, Kowalski P, Kowalska T, Duszyńska B, Charakchieva-Minol S, Tatarczyńska E, Kłodzińska A, Chojnacka-Wójcik E. Bojarski AJ, et al. Bioorg Med Chem. 2002 Dec;10(12):3817-27. doi: 10.1016/s0968-0896(02)00349-8. Bioorg Med Chem. 2002. PMID: 12413835
1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), alpha1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics.
Bojarski AJ, Paluchowska MH, Duszyńska B, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E. Bojarski AJ, et al. Bioorg Med Chem. 2005 Mar 15;13(6):2293-303. doi: 10.1016/j.bmc.2004.12.041. Bioorg Med Chem. 2005. PMID: 15727878
Structure-intrinsic activity relationship studies in the group of 1-imido/amido substituted 4-(4-arylpiperazin-1-yl)cyclohexane derivatives; new, potent 5-HT1A receptor agents with anxiolytic- like activity.
Bojarski AJ, Paluchowska MH, Duszyńska B, Bugno R, Kłodzińska A, Tatarczyńska E, Chojnacka-Wójcik E. Bojarski AJ, et al. Bioorg Med Chem. 2006 Mar 1;14(5):1391-402. doi: 10.1016/j.bmc.2005.09.060. Epub 2005 Nov 2. Bioorg Med Chem. 2006. PMID: 16266808
The influence of modifications in imide fragment structure on 5-HT(1A) and 5-HT(7) receptor affinity and in vivo pharmacological properties of some new 1-(m-trifluoromethylphenyl)piperazines.
Paluchowska MH, Bugno R, Duszyńska B, Tatarczyńska E, Nikiforuk A, Lenda T, Chojnacka-Wójcik E. Paluchowska MH, et al. Among authors: chojnacka wojcik e. Bioorg Med Chem. 2007 Nov 15;15(22):7116-25. doi: 10.1016/j.bmc.2007.07.029. Epub 2007 Aug 22. Bioorg Med Chem. 2007. PMID: 17825569
Synthesis and pharmacological evaluation of new 5-(cyclo)alkyl-5-phenyl- and 5-spiroimidazolidine-2,4-dione derivatives. Novel 5-HT1A receptor agonist with potential antidepressant and anxiolytic activity.
Czopek A, Byrtus H, Kołaczkowski M, Pawłowski M, Dybała M, Nowak G, Tatarczyńska E, Wesołowska A, Chojnacka-Wójcik E. Czopek A, et al. Among authors: chojnacka wojcik e. Eur J Med Chem. 2010 Apr;45(4):1295-303. doi: 10.1016/j.ejmech.2009.11.053. Epub 2009 Dec 6. Eur J Med Chem. 2010. PMID: 20060623
150 results