Wilson KP - Search Results

1

Structure and mechanism of inosine monophosphate dehydrogenase in complex with the immunosuppressant mycophenolic acid.

Sintchak MD, Fleming MA, Futer O, Raybuck SA, Chambers SP, Caron PR, Murcko MA, Wilson KP. Sintchak MD, et al. Among authors: wilson kp. Cell. 1996 Jun 14;85(6):921-30. doi: 10.1016/s0092-8674(00)81275-1. Cell. 1996. PMID: 8681386 Free article.

2

Structure and mechanism of interleukin-1 beta converting enzyme.

Wilson KP, Black JA, Thomson JA, Kim EE, Griffith JP, Navia MA, Murcko MA, Chambers SP, Aldape RA, Raybuck SA, et al. Wilson KP, et al. Nature. 1994 Jul 28;370(6487):270-5. doi: 10.1038/370270a0. Nature. 1994. PMID: 8035875

3

Inhibition of IMPDH by mycophenolic acid: dissection of forward and reverse pathways using capillary electrophoresis.

Fleming MA, Chambers SP, Connelly PR, Nimmesgern E, Fox T, Bruzzese FJ, Hoe ST, Fulghum JR, Livingston DJ, Stuver CM, Sintchak MD, Wilson KP, Thomson JA. Fleming MA, et al. Among authors: wilson kp. Biochemistry. 1996 Jun 4;35(22):6990-7. doi: 10.1021/bi9607416. Biochemistry. 1996. PMID: 8679523

4

Crystal structure of p38 mitogen-activated protein kinase.

Wilson KP, Fitzgibbon MJ, Caron PR, Griffith JP, Chen W, McCaffrey PG, Chambers SP, Su MS. Wilson KP, et al. J Biol Chem. 1996 Nov 1;271(44):27696-700. doi: 10.1074/jbc.271.44.27696. J Biol Chem. 1996. PMID: 8910361 Free article.

5

Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases.

Margolin N, Raybuck SA, Wilson KP, Chen W, Fox T, Gu Y, Livingston DJ. Margolin N, et al. Among authors: wilson kp. J Biol Chem. 1997 Mar 14;272(11):7223-8. doi: 10.1074/jbc.272.11.7223. J Biol Chem. 1997. PMID: 9054418 Free article.

6

The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase.

Wilson KP, McCaffrey PG, Hsiao K, Pazhanisamy S, Galullo V, Bemis GW, Fitzgibbon MJ, Caron PR, Murcko MA, Su MS. Wilson KP, et al. Chem Biol. 1997 Jun;4(6):423-31. doi: 10.1016/s1074-5521(97)90194-0. Chem Biol. 1997. PMID: 9224565

7

Crystal structure of JNK3: a kinase implicated in neuronal apoptosis.

Xie X, Gu Y, Fox T, Coll JT, Fleming MA, Markland W, Caron PR, Wilson KP, Su MS. Xie X, et al. Among authors: wilson kp. Structure. 1998 Aug 15;6(8):983-91. doi: 10.1016/s0969-2126(98)00100-2. Structure. 1998. PMID: 9739089 Free article.

8

Comparative X-ray structures of the major binding protein for the immunosuppressant FK506 (tacrolimus) in unliganded form and in complex with FK506 and rapamycin.

Wilson KP, Yamashita MM, Sintchak MD, Rotstein SH, Murcko MA, Boger J, Thomson JA, Fitzgibbon MJ, Black JR, Navia MA. Wilson KP, et al. Acta Crystallogr D Biol Crystallogr. 1995 Jul 1;51(Pt 4):511-21. doi: 10.1107/S0907444994014514. Acta Crystallogr D Biol Crystallogr. 1995. PMID: 15299838

9

A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase.

Fox T, Coll JT, Xie X, Ford PJ, Germann UA, Porter MD, Pazhanisamy S, Fleming MA, Galullo V, Su MS, Wilson KP. Fox T, et al. Among authors: wilson kp. Protein Sci. 1998 Nov;7(11):2249-55. doi: 10.1002/pro.5560071102. Protein Sci. 1998. PMID: 9827991 Free PMC article.

10

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity.

Wei Y, Fox T, Chambers SP, Sintchak J, Coll JT, Golec JM, Swenson L, Wilson KP, Charifson PS. Wei Y, et al. Among authors: wilson kp. Chem Biol. 2000 Jun;7(6):423-32. doi: 10.1016/s1074-5521(00)00123-x. Chem Biol. 2000. PMID: 10873833

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