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Japanese individuals do not harbor the T594M mutation but do have the P592S mutation in the C-terminus of the beta-subunit of the epithelial sodium channel: the Ohasama study.
Matsubara M, Ohkubo T, Michimata M, Hozawa A, Ishikawa K, Katsuya T, Nagai K, Tsuji I, Higaki J, Araki T, Satoh H, Hisamichi S, Ito S, Ogihara T, Imai Y. Matsubara M, et al. Among authors: ohkubo t. J Hypertens. 2000 Jul;18(7):861-6. doi: 10.1097/00004872-200018070-00007. J Hypertens. 2000. PMID: 10930183 Clinical Trial.
Aldosterone synthase gene (CYP11B2) C-334T polymorphism, ambulatory blood pressure and nocturnal decline in blood pressure in the general Japanese population: the Ohasama Study.
Matsubara M, Kikuya M, Ohkubo T, Metoki H, Omori F, Fujiwara T, Suzuki M, Michimata M, Hozawa A, Katsuya T, Higaki J, Tsuji I, Araki T, Ogihara T, Satoh H, Hisamichi S, Nagai K, Kitaoka H, Imai Y. Matsubara M, et al. Among authors: ohkubo t. J Hypertens. 2001 Dec;19(12):2179-84. doi: 10.1097/00004872-200112000-00010. J Hypertens. 2001. PMID: 11725161
1,599 results