Kinney WA - Search Results

1

The synthesis and characterization of analogs of the antimicrobial compound squalamine: 6 beta-hydroxy-3-aminosterols synthesized from hyodeoxycholic acid.

Jones SR, Kinney WA, Zhang X, Jones LM, Selinsky BS. Jones SR, et al. Among authors: kinney wa. Steroids. 1996 Oct;61(10):565-71. doi: 10.1016/s0039-128x(96)00114-6. Steroids. 1996. PMID: 8910969

2

The synthesis of spermine analogs of the shark aminosterol squalamine.

Shu Y, Jones SR, Kinney WA, Selinsky BS. Shu Y, et al. Among authors: kinney wa. Steroids. 2002 Mar;67(3-4):291-304. doi: 10.1016/s0039-128x(01)00161-1. Steroids. 2002. PMID: 11856553

3

Aminosterols from the dogfish shark Squalus acanthias.

Rao MN, Shinnar AE, Noecker LA, Chao TL, Feibush B, Snyder B, Sharkansky I, Sarkahian A, Zhang X, Jones SR, Kinney WA, Zasloff M. Rao MN, et al. Among authors: kinney wa. J Nat Prod. 2000 May;63(5):631-5. doi: 10.1021/np990514f. J Nat Prod. 2000. PMID: 10843574

4

A short formal synthesis of squalamine from a microbial metabolite.

Kinney WA, Zhang X, Williams JI, Johnston S, Michalak RS, Deshpande M, Dostal L, Rosazza JP. Kinney WA, et al. Org Lett. 2000 Sep 21;2(19):2921-2. doi: 10.1021/ol0059495. Org Lett. 2000. PMID: 10986072

5

A spermine-coupled cholesterol metabolite from the shark with potent appetite suppressant and antidiabetic properties.

Zasloff M, Williams JI, Chen Q, Anderson M, Maeder T, Holroyd K, Jones S, Kinney W, Cheshire K, McLane M. Zasloff M, et al. Int J Obes Relat Metab Disord. 2001 May;25(5):689-97. doi: 10.1038/sj.ijo.0801599. Int J Obes Relat Metab Disord. 2001. PMID: 11360152

6

Practical Approaches to Remote Asymmetric Induction in Steroidal Side-Chains Utilizing Oxazaborolidine Reagents.

Rao MN, McGuigan MA, Zhang X, Shaked Z, Kinney WA, Bulliard M, Laboue B, Lee NE. Rao MN, et al. Among authors: kinney wa. J Org Chem. 1997 Jun 27;62(13):4541-4545. doi: 10.1021/jo970227l. J Org Chem. 1997. PMID: 11671794 No abstract available.

7

Ester Prodrugs of IHVR-19029 with Enhanced Oral Exposure and Prevention of Gastrointestinal Glucosidase Interaction.

Ma J, Wu S, Zhang X, Guo F, Yang K, Guo J, Su Q, Lu H, Lam P, Li Y, Yan Z, Kinney W, Guo JT, Block TM, Chang J, Du Y. Ma J, et al. ACS Med Chem Lett. 2017 Jan 17;8(2):157-162. doi: 10.1021/acsmedchemlett.6b00332. eCollection 2017 Feb 9. ACS Med Chem Lett. 2017. PMID: 28197304 Free PMC article.

8

Squalamine inhibits angiogenesis and solid tumor growth in vivo and perturbs embryonic vasculature.

Sills AK Jr, Williams JI, Tyler BM, Epstein DS, Sipos EP, Davis JD, McLane MP, Pitchford S, Cheshire K, Gannon FH, Kinney WA, Chao TL, Donowitz M, Laterra J, Zasloff M, Brem H. Sills AK Jr, et al. Among authors: kinney wa. Cancer Res. 1998 Jul 1;58(13):2784-92. Cancer Res. 1998. PMID: 9661892

9

Bioisosteric replacement of the alpha-amino carboxylic acid functionality in 2-amino-5-phosphonopentanoic acid yields unique 3,4-diamino-3-cyclobutene-1,2-dione containing NMDA antagonists.

Kinney WA, Lee NE, Garrison DT, Podlesny EJ Jr, Simmonds JT, Bramlett D, Notvest RR, Kowal DM, Tasse RP. Kinney WA, et al. J Med Chem. 1992 Dec 11;35(25):4720-6. doi: 10.1021/jm00103a010. J Med Chem. 1992. PMID: 1361582

10

N-phenyl-2-pyridinecarbothioamides as gastric mucosal protectants.

Kinney WA, Lee NE, Blank RM, Demerson CA, Sarnella CS, Scherer NT, Mir GN, Borella LE, DiJoseph JF, Wells C. Kinney WA, et al. J Med Chem. 1990 Jan;33(1):327-36. doi: 10.1021/jm00163a053. J Med Chem. 1990. PMID: 2296028

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