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Identification and active expression of the Mycobacterium tuberculosis gene encoding 5-phospho-{alpha}-d-ribose-1-diphosphate: decaprenyl-phosphate 5-phosphoribosyltransferase, the first enzyme committed to decaprenylphosphoryl-d-arabinose synthesis.
Huang H, Scherman MS, D'Haeze W, Vereecke D, Holsters M, Crick DC, McNeil MR. Huang H, et al. Among authors: scherman ms. J Biol Chem. 2005 Jul 1;280(26):24539-43. doi: 10.1074/jbc.M504068200. Epub 2005 May 4. J Biol Chem. 2005. PMID: 15878857 Free article.
The identification and location of succinyl residues and the characterization of the interior arabinan region allow for a model of the complete primary structure of Mycobacterium tuberculosis mycolyl arabinogalactan.
Bhamidi S, Scherman MS, Rithner CD, Prenni JE, Chatterjee D, Khoo KH, McNeil MR. Bhamidi S, et al. Among authors: scherman ms. J Biol Chem. 2008 May 9;283(19):12992-3000. doi: 10.1074/jbc.M800222200. Epub 2008 Feb 26. J Biol Chem. 2008. PMID: 18303028 Free PMC article.
Biosynthetic origin of mycobacterial cell wall arabinosyl residues.
Scherman M, Weston A, Duncan K, Whittington A, Upton R, Deng L, Comber R, Friedrich JD, McNeil M. Scherman M, et al. J Bacteriol. 1995 Dec;177(24):7125-30. doi: 10.1128/jb.177.24.7125-7130.1995. J Bacteriol. 1995. PMID: 8522519 Free PMC article.
Determination of the pathway for rhamnose biosynthesis in mycobacteria: cloning, sequencing and expression of the Mycobacterium tuberculosis gene encoding alpha-D-glucose-1-phosphate thymidylyltransferase.
Ma Y, Mills JA, Belisle JT, Vissa V, Howell M, Bowlin K, Scherman MS, McNeil M. Ma Y, et al. Among authors: scherman ms. Microbiology (Reading). 1997 Mar;143 ( Pt 3):937-945. doi: 10.1099/00221287-143-3-937. Microbiology (Reading). 1997. PMID: 9084178 Free article.
Inactivation of the mycobacterial rhamnosyltransferase, which is needed for the formation of the arabinogalactan-peptidoglycan linker, leads to irreversible loss of viability.
Mills JA, Motichka K, Jucker M, Wu HP, Uhlik BC, Stern RJ, Scherman MS, Vissa VD, Pan F, Kundu M, Ma YF, McNeil M. Mills JA, et al. Among authors: scherman ms. J Biol Chem. 2004 Oct 15;279(42):43540-6. doi: 10.1074/jbc.M407782200. Epub 2004 Aug 4. J Biol Chem. 2004. PMID: 15294902 Free article.
45 results