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How are the regulators regulated? The search for mechanisms that impose specificity on induction of cell death and NF-kappaB activation by members of the TNF/NGF receptor family.
Wallach D, Arumugam TU, Boldin MP, Cantarella G, Ganesh KA, Goltsev Y, Goncharov TM, Kovalenko AV, Rajput A, Varfolomeev EE, Zhang SQ. Wallach D, et al. Arthritis Res. 2002;4 Suppl 3(Suppl 3):S189-96. doi: 10.1186/ar585. Epub 2002 May 9. Arthritis Res. 2002. PMID: 12110139 Free PMC article. Review.
Targeted disruption of the mouse Caspase 8 gene ablates cell death induction by the TNF receptors, Fas/Apo1, and DR3 and is lethal prenatally.
Varfolomeev EE, Schuchmann M, Luria V, Chiannilkulchai N, Beckmann JS, Mett IL, Rebrikov D, Brodianski VM, Kemper OC, Kollet O, Lapidot T, Soffer D, Sobe T, Avraham KB, Goncharov T, Holtmann H, Lonai P, Wallach D. Varfolomeev EE, et al. Among authors: goncharov t. Immunity. 1998 Aug;9(2):267-76. doi: 10.1016/s1074-7613(00)80609-3. Immunity. 1998. PMID: 9729047 Free article.
Transcription-controlled gene therapy against tumor angiogenesis.
Greenberger S, Shaish A, Varda-Bloom N, Levanon K, Breitbart E, Goldberg I, Barshack I, Hodish I, Yaacov N, Bangio L, Goncharov T, Wallach D, Harats D. Greenberger S, et al. Among authors: goncharov t. J Clin Invest. 2004 Apr;113(7):1017-24. doi: 10.1172/JCI20007. J Clin Invest. 2004. PMID: 15057308 Free PMC article.
Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects.
Prado-Acosta M, Jeong S, Utrero-Rico A, Goncharov T, Webster JD, Holler E, Morales G, Dellepiane S, Levine JE, Rothenberg ME, Vucic D, Ferrara JLM. Prado-Acosta M, et al. Among authors: goncharov t. Sci Transl Med. 2023 Dec 20;15(727):eadf8366. doi: 10.1126/scitranslmed.adf8366. Epub 2023 Dec 20. Sci Transl Med. 2023. PMID: 38117900 Free PMC article.
31 results