Hawley SR - Search Results

1

Physicochemical properties correlated with drug resistance and the reversal of drug resistance in Plasmodium falciparum.

Bray PG, Hawley SR, Mungthin M, Ward SA. Bray PG, et al. Among authors: hawley sr. Mol Pharmacol. 1996 Dec;50(6):1559-66. Mol Pharmacol. 1996. PMID: 8967978

2

Current views on the mechanisms of resistance to quinoline-containing drugs in Plasmodium falciparum.

Ward SA, Bray PG, Mungthin M, Hawley SR. Ward SA, et al. Among authors: hawley sr. Ann Trop Med Parasitol. 1995 Apr;89(2):121-4. doi: 10.1080/00034983.1995.11812942. Ann Trop Med Parasitol. 1995. PMID: 7605121

3

The role of drug accumulation in 4-aminoquinoline antimalarial potency. The influence of structural substitution and physicochemical properties.

Hawley SR, Bray PG, O'Neill PM, Park BK, Ward SA. Hawley SR, et al. Biochem Pharmacol. 1996 Sep 13;52(5):723-33. doi: 10.1016/0006-2952(96)00354-1. Biochem Pharmacol. 1996. PMID: 8765470

4

Amodiaquine accumulation in Plasmodium falciparum as a possible explanation for its superior antimalarial activity over chloroquine.

Hawley SR, Bray PG, Park BK, Ward SA. Hawley SR, et al. Mol Biochem Parasitol. 1996 Sep;80(1):15-25. doi: 10.1016/0166-6851(96)02655-2. Mol Biochem Parasitol. 1996. PMID: 8885219

5

Manipulation of the N-alkyl substituent in amodiaquine to overcome the verapamil-sensitive chloroquine resistance component.

Hawley SR, Bray PG, O'Neill PM, Naisbitt DJ, Park BK, Ward SA. Hawley SR, et al. Antimicrob Agents Chemother. 1996 Oct;40(10):2345-9. doi: 10.1128/AAC.40.10.2345. Antimicrob Agents Chemother. 1996. PMID: 8891142 Free PMC article.

6

4-Aminoquinoline resistance of Plasmodium falciparum: insights from the study of amodiaquine uptake.

Bray PG, Hawley SR, Ward SA. Bray PG, et al. Among authors: hawley sr. Mol Pharmacol. 1996 Dec;50(6):1551-8. Mol Pharmacol. 1996. PMID: 8967977

7

In vitro selection of halofantrine resistance in Plasmodium falciparum is not associated with increased expression of Pgh1.

Ritchie GY, Mungthin M, Green JE, Bray PG, Hawley SR, Ward SA. Ritchie GY, et al. Among authors: hawley sr. Mol Biochem Parasitol. 1996 Dec 2;83(1):35-46. doi: 10.1016/s0166-6851(96)02746-6. Mol Biochem Parasitol. 1996. PMID: 9010840

8

Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues.

O'Neill PM, Willock DJ, Hawley SR, Bray PG, Storr RC, Ward SA, Park BK. O'Neill PM, et al. Among authors: hawley sr. J Med Chem. 1997 Feb 14;40(4):437-48. doi: 10.1021/jm960370r. J Med Chem. 1997. PMID: 9046333

9

Quinoline resistance mechanisms in Plasmodium falciparum: the debate goes on.

Ward SA, Bray PG, Hawley SR. Ward SA, et al. Among authors: hawley sr. Parasitology. 1997;114 Suppl:S125-36. Parasitology. 1997. PMID: 9309774 Review.

10

4-Aminoquinolines--past, present, and future: a chemical perspective.

O'Neill PM, Bray PG, Hawley SR, Ward SA, Park BK. O'Neill PM, et al. Among authors: hawley sr. Pharmacol Ther. 1998 Jan;77(1):29-58. doi: 10.1016/s0163-7258(97)00084-3. Pharmacol Ther. 1998. PMID: 9500158 Review.

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