Shockcor JP - Search Results

1

Combined HPLC, NMR spectroscopy, and ion-trap mass spectrometry with application to the detection and characterization of xenobiotic and endogenous metabolites in human urine.

Shockcor JP, Unger SE, Wilson ID, Foxall PJ, Nicholson JK, Lindon JC. Shockcor JP, et al. Anal Chem. 1996 Dec 15;68(24):4431-5. doi: 10.1021/ac9606463. Anal Chem. 1996. PMID: 8972626

2

Characterization of in vitro metabolites from human liver microsomes using directly coupled hplc-nmr: application to a phenoxathiin monoamine oxidase-A inhibitor.

Shockcor JP, Silver IS, Wurm RM, Sanderson PN, Farrant RD, Sweatman BC, Lindon JC. Shockcor JP, et al. Xenobiotica. 1996 Jan;26(1):41-8. doi: 10.3109/00498259609046687. Xenobiotica. 1996. PMID: 8851820

3

Hplc-nmr identification of the human urinary metabolites of (-)-cis-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl] cytosine, a nucleoside analogue active against human immunodeficiency virus (HIV).

Shockcor JP, Wurm RM, Frick LW, Sanderson PN, Farrant RD, Sweatman BC, Lindon JC. Shockcor JP, et al. Xenobiotica. 1996 Feb;26(2):189-99. doi: 10.3109/00498259609046699. Xenobiotica. 1996. PMID: 8868002 Clinical Trial.

4

The conformational behaviour of the cardiac glycoside digoxin as indicated by NMR spectroscopy and molecular dynamics calculations.

Aulabaugh AE, Crouch RC, Martin GE, Ragouzeos A, Shockcor JP, Spitzer TD, Farrant RD, Hudson BD, Lindon JC. Aulabaugh AE, et al. Among authors: shockcor jp. Carbohydr Res. 1992 Jun 16;230(2):201-12. doi: 10.1016/0008-6215(92)84033-o. Carbohydr Res. 1992. PMID: 1394296

5

NMR and HPLC-NMR spectroscopic studies of futile deacetylation in paracetamol metabolites in rat and man.

Nicholls AW, Farrant RD, Shockcor JP, Unger SE, Wilson ID, Lindon JC, Nicholson JK. Nicholls AW, et al. Among authors: shockcor jp. J Pharm Biomed Anal. 1997 Apr;15(7):901-10. doi: 10.1016/s0731-7085(96)01950-4. J Pharm Biomed Anal. 1997. PMID: 9160256

6

Directly-coupled HPLC-NMR spectroscopic studies of metabolism and futile deacetylation of phenacetin in the rat.

Nicholls AW, Lindon JC, Farrant RD, Shockcor JP, Wilson ID, Nicholson JK. Nicholls AW, et al. Among authors: shockcor jp. J Pharm Biomed Anal. 1999 Sep;20(6):865-73. doi: 10.1016/s0731-7085(99)00104-1. J Pharm Biomed Anal. 1999. PMID: 10746955

7

Application of directly coupled LC-NMR-MS to the structural elucidation of metabolites of the HIV-1 reverse-transcriptase inhibitor BW935U83.

Shockcor JP, Unger SE, Savina P, Nicholson JK, Lindon JC. Shockcor JP, et al. J Chromatogr B Biomed Sci Appl. 2000 Oct 1;748(1):269-79. doi: 10.1016/s0378-4347(00)00360-1. J Chromatogr B Biomed Sci Appl. 2000. PMID: 11092604

8

Directly coupled HPLC-NMR and HPLC-MS approaches for the rapid characterisation of drug metabolites in urine: application to the human metabolism of naproxen.

Sidelmann UG, Bjørnsdottir I, Shockcor JP, Hansen SH, Lindon JC, Nicholson JK. Sidelmann UG, et al. Among authors: shockcor jp. J Pharm Biomed Anal. 2001 Feb;24(4):569-79. doi: 10.1016/s0731-7085(00)00482-9. J Pharm Biomed Anal. 2001. PMID: 11272313

9

Identification of phenacetin metabolites in human urine after administration of phenacetin-C2H3: measurement of futile metabolic deacetylation via HPLC/MS-SPE-NMR and HPLC-ToF MS.

Nicholls AW, Wilson ID, Godejohann M, Nicholson JK, Shockcor JP. Nicholls AW, et al. Among authors: shockcor jp. Xenobiotica. 2006 Jul;36(7):615-29. doi: 10.1080/00498250600711113. Xenobiotica. 2006. PMID: 16864507

10

The application of microbore UPLC/oa-TOF-MS and 1H NMR spectroscopy to the metabonomic analysis of rat urine following the intravenous administration of pravastatin.

Lenz EM, Williams RE, Sidaway J, Smith BW, Plumb RS, Johnson KA, Rainville P, Shockcor J, Stumpf CL, Granger JH, Wilson ID. Lenz EM, et al. J Pharm Biomed Anal. 2007 Aug 15;44(4):845-52. doi: 10.1016/j.jpba.2007.04.035. Epub 2007 May 3. J Pharm Biomed Anal. 2007. PMID: 17561363

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