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Intracerebroventricular administration of GM1 ganglioside to presenile Alzheimer patients.
Augustinsson LE, Blennow K, Blomstrand C, Bråne G, Ekman R, Fredman P, Karlsson I, Kihlgren M, Lehmann W, Lekman A, Månsson JE, Ramström I, Wallin A, Wikkelsö C, Gottfries CG, Svennerholm L. Augustinsson LE, et al. Among authors: fredman p. Dement Geriatr Cogn Disord. 1997 Jan-Feb;8(1):26-33. doi: 10.1159/000106597. Dement Geriatr Cogn Disord. 1997. PMID: 8997549 Clinical Trial.
Structural membrane alterations in Alzheimer brains found to be associated with regional disease development; increased density of gangliosides GM1 and GM2 and loss of cholesterol in detergent-resistant membrane domains.
Molander-Melin M, Blennow K, Bogdanovic N, Dellheden B, Månsson JE, Fredman P. Molander-Melin M, et al. Among authors: fredman p. J Neurochem. 2005 Jan;92(1):171-82. doi: 10.1111/j.1471-4159.2004.02849.x. J Neurochem. 2005. PMID: 15606906 Free article.
Gangliosides in cerebrospinal fluid in 'probable Alzheimer's disease'.
Blennow K, Davidsson P, Wallin A, Fredman P, Gottfries CG, Karlsson I, Månsson JE, Svennerholm L. Blennow K, et al. Among authors: fredman p. Arch Neurol. 1991 Oct;48(10):1032-5. doi: 10.1001/archneur.1991.00530220048018. Arch Neurol. 1991. PMID: 1929894
177 results