Zhang H - Search Results

1

Prevention of simian immunodeficiency virus, SIVsm, or HIV-2 infection in cynomolgus monkeys by pre- and postexposure administration of BEA-005.

Böttiger D, Johansson NG, Samuelsson B, Zhang H, Putkonen P, Vrang L, Oberg B. Böttiger D, et al. Among authors: zhang h. AIDS. 1997 Feb;11(2):157-62. doi: 10.1097/00002030-199702000-00004. AIDS. 1997. PMID: 9030361

2

Inhibition of human immunodeficiency virus type 1 wild-type and mutant reverse transcriptases by the phenyl ethyl thiazolyl thiourea derivatives trovirdine and MSC-127.

Zhang H, Vrang L, Bäckbro K, Lind P, Sahlberg C, Unge T, Oberg B. Zhang H, et al. Antiviral Res. 1995 Dec;28(4):331-42. doi: 10.1016/0166-3542(95)00056-9. Antiviral Res. 1995. PMID: 8669892

3

Enzymatic properties and sensitivity to inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase with Glu-138-->Arg and Tyr-188-->His mutations.

Zhang H, Vrang L, Bäckbro K, Unge T, Noréen R, Oberg B. Zhang H, et al. Antiviral Res. 1994 May;24(1):43-57. doi: 10.1016/0166-3542(94)90051-5. Antiviral Res. 1994. PMID: 7524439

4

Disruption of a salt bridge between Asp 488 and Lys 465 in HIV-1 reverse transcriptase alters its proteolytic processing and polymerase activity.

Goobar-Larsson L, Bäckbro K, Unge T, Bhikhabhai R, Vrang L, Zhang H, Orvell C, Strandberg B, Oberg B. Goobar-Larsson L, et al. Among authors: zhang h. Virology. 1993 Oct;196(2):731-8. doi: 10.1006/viro.1993.1530. Virology. 1993. PMID: 7690504

5

Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues.

Högberg M, Sahlberg C, Engelhardt P, Noréen R, Kangasmetsä J, Johansson NG, Oberg B, Vrang L, Zhang H, Sahlberg BL, Unge T, Lövgren S, Fridborg K, Bäckbro K. Högberg M, et al. Among authors: zhang h. J Med Chem. 1999 Oct 7;42(20):4150-60. doi: 10.1021/jm990095j. J Med Chem. 1999. PMID: 10514285

6

Bioisosteric modification of PETT-HIV-1 RT-inhibitors: synthesis and biological evaluation.

Högberg M, Engelhardt P, Vrang L, Zhang H. Högberg M, et al. Among authors: zhang h. Bioorg Med Chem Lett. 2000 Feb 7;10(3):265-8. doi: 10.1016/s0960-894x(99)00675-7. Bioorg Med Chem Lett. 2000. PMID: 10698450

7

Phenethylthiazolylthiourea (PETT) compounds as a new class of HIV-1 reverse transcriptase inhibitors. 2. Synthesis and further structure-activity relationship studies of PETT analogs.

Cantrell AS, Engelhardt P, Högberg M, Jaskunas SR, Johansson NG, Jordan CL, Kangasmetsä J, Kinnick MD, Lind P, Morin JM Jr, Muesing MA, Noreén R, Oberg B, Pranc P, Sahlberg C, Ternansky RJ, Vasileff RT, Vrang L, West SJ, Zhang H. Cantrell AS, et al. Among authors: zhang h. J Med Chem. 1996 Oct 11;39(21):4261-74. doi: 10.1021/jm950639r. J Med Chem. 1996. PMID: 8863804

8

Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro- 5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)]-beta-D-pentofurano syl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleoside inhibitors.

Balzarini J, Karlsson A, Vandamme AM, Pérez-Pérez MJ, Zhang H, Vrang L, Oberg B, Bäckbro K, Unge T, San-Félix A, et al. Balzarini J, et al. Among authors: zhang h. Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):6952-6. doi: 10.1073/pnas.90.15.6952. Proc Natl Acad Sci U S A. 1993. PMID: 7688467 Free PMC article.

9

Design and synthesis of potent C(2)-symmetric diol-based HIV-1 protease inhibitors: effects of fluoro substitution.

Pyring D, Lindberg J, Rosenquist A, Zuccarello G, Kvarnström I, Zhang H, Vrang L, Unge T, Classon B, Hallberg A, Samuelsson B. Pyring D, et al. Among authors: zhang h. J Med Chem. 2001 Sep 13;44(19):3083-91. doi: 10.1021/jm001134q. J Med Chem. 2001. PMID: 11543677

10

Synthesis and anti-HIV activities of urea-PETT analogs belonging to a new class of potent non-nucleoside HIV-1 reverse transcriptase inhibitors.

Sahlberg C, Noréen R, Engelhardt P, Högberg M, Kangasmetsä J, Vrang L, Zhang H. Sahlberg C, et al. Among authors: zhang h. Bioorg Med Chem Lett. 1998 Jun 16;8(12):1511-6. doi: 10.1016/s0960-894x(98)00249-2. Bioorg Med Chem Lett. 1998. PMID: 9873380

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