Scandella D - Search Results

1

Anti-factor VIII inhibitor alloantibodies recognizing the A2 domain in the human factor VIII heavy chain poorly bind to porcine factor VIII.

Sawamoto Y, Shima M, Tanaka I, Nakai H, Kamisue S, Scandella D, Yoshioka A. Sawamoto Y, et al. Among authors: scandella d. Int J Hematol. 1997 Feb;65(2):151-8. doi: 10.1016/s0925-5710(96)00555-5. Int J Hematol. 1997. PMID: 9071819

2

A factor VIII neutralizing monoclonal antibody and a human inhibitor alloantibody recognizing epitopes in the C2 domain inhibit factor VIII binding to von Willebrand factor and to phosphatidylserine.

Shima M, Scandella D, Yoshioka A, Nakai H, Tanaka I, Kamisue S, Terada S, Fukui H. Shima M, et al. Among authors: scandella d. Thromb Haemost. 1993 Mar 1;69(3):240-6. Thromb Haemost. 1993. PMID: 7682339

3

Common inhibitory effects of human anti-C2 domain inhibitor alloantibodies on factor VIII binding to von Willebrand factor.

Shima M, Nakai H, Scandella D, Tanaka I, Sawamoto Y, Kamisue S, Morichika S, Murakami T, Yoshioka A. Shima M, et al. Among authors: scandella d. Br J Haematol. 1995 Nov;91(3):714-21. doi: 10.1111/j.1365-2141.1995.tb05374.x. Br J Haematol. 1995. PMID: 8555081

4

Identification of a factor VIII peptide, residues 2315-2330, which neutralizes human factor VIII C2 inhibitor alloantibodies: requirement of Cys2326 and Glu2327 for maximum effect.

Nogami K, Shima M, Nakai H, Tanaka I, Suzuki H, Morichika S, Shibata M, Saenko EL, Scandella D, Giddings JC, Yoshioka A. Nogami K, et al. Among authors: scandella d. Br J Haematol. 1999 Oct;107(1):196-203. doi: 10.1046/j.1365-2141.1999.01673.x. Br J Haematol. 1999. PMID: 10520041 Free article.

5

Role of factor VIII C2 domain in factor VIII binding to factor Xa.

Nogami K, Shima M, Hosokawa K, Suzuki T, Koide T, Saenko EL, Scandella D, Shibata M, Kamisue S, Tanaka I, Yoshioka A. Nogami K, et al. Among authors: scandella d. J Biol Chem. 1999 Oct 22;274(43):31000-7. doi: 10.1074/jbc.274.43.31000. J Biol Chem. 1999. PMID: 10521497 Free article.

6

An alloantibody recognizing the FVIII A1 domain in a patient with CRM reduced haemophilia A due to deletion of a large portion of the A1 domain DNA sequence.

Shibata M, Shima M, Morichika S, McVey J, Tuddenham EG, Tanaka I, Suzuki H, Nogami K, Minamoto Y, Hato T, Saenko EL, Scandella D, Yoshioka A. Shibata M, et al. Among authors: scandella d. Thromb Haemost. 2000 Sep;84(3):442-8. Thromb Haemost. 2000. PMID: 11019969

7

In hemophilia A and autoantibody inhibitor patients: the factor VIII A2 domain and light chain are most immunogenic.

Scandella DH, Nakai H, Felch M, Mondorf W, Scharrer I, Hoyer LW, Saenko EL. Scandella DH, et al. Thromb Res. 2001 Mar 1;101(5):377-85. doi: 10.1016/s0049-3848(00)00418-7. Thromb Res. 2001. PMID: 11297754

8

Residues 484-508 contain a major determinant of the inhibitory epitope in the A2 domain of human factor VIII.

Healey JF, Lubin IM, Nakai H, Saenko EL, Hoyer LW, Scandella D, Lollar P. Healey JF, et al. Among authors: scandella d. J Biol Chem. 1995 Jun 16;270(24):14505-9. doi: 10.1074/jbc.270.24.14505. J Biol Chem. 1995. PMID: 7540171 Free article.

9

Slowed release of thrombin-cleaved factor VIII from von Willebrand factor by a monoclonal and a human antibody is a novel mechanism for factor VIII inhibition.

Saenko EL, Shima M, Gilbert GE, Scandella D. Saenko EL, et al. Among authors: scandella d. J Biol Chem. 1996 Nov 1;271(44):27424-31. doi: 10.1074/jbc.271.44.27424. J Biol Chem. 1996. PMID: 8910322 Free article.

10

Dominant C2 domain epitope specificity of inhibitor antibodies elicited by a heat pasteurized product, factor VIII CPS-P, in previously treated hemophilia A patients without inhibitors.

Sawamoto Y, Prescott R, Zhong D, Saenko EL, Mauser-Bunschoten E, Peerlinck K, van den Berg M, Scandella D. Sawamoto Y, et al. Among authors: scandella d. Thromb Haemost. 1998 Jan;79(1):62-8. Thromb Haemost. 1998. PMID: 9459325

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