Nakamura A - Search Results

1

Pharmacokinetics of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate. 3rd communication: plasma concentrations of the unchanged drug and its deethylated metabolite in rats, dogs and monkeys.

Nakamura A, Hirota T, Sugihara K, Morino A. Nakamura A, et al. Arzneimittelforschung. 1997 Feb;47(2):169-74. Arzneimittelforschung. 1997. PMID: 9079236

2

Pharmacokinetics of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate. 4th communication: metabolism in rats and dogs.

Hirota T, Nakamura A, Sugihara K, Morino A. Hirota T, et al. Among authors: nakamura a. Arzneimittelforschung. 1997 Feb;47(2):175-81. Arzneimittelforschung. 1997. PMID: 9079237

3

Cytochrome P450 isoforms responsible for the N-deethylation and cyclohexane-hydroxylation of NS-21.

Nakamura A, Hirota T, Morino A, Imaoka S, Funae Y, Yamamoto Y, Tasaki T, Masuda M, Kazusaka A, Fujita S. Nakamura A, et al. Xenobiotica. 1999 Mar;29(3):243-52. doi: 10.1080/004982599238641. Xenobiotica. 1999. PMID: 10219965

4

Pharmacokinetics of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate. 1st communication: absorption, distribution and excretion after single administration of 14C-labeled compound to rats and dogs.

Nakamura A, Sugihara K, Hirota T, Morino A, Ezumi Y, Takaichi M. Nakamura A, et al. Arzneimittelforschung. 1997 Feb;47(2):151-9. Arzneimittelforschung. 1997. PMID: 9079234

5

Pharmacokinetics of (+/-)-4-diethylamino-1,1-dimethylbut-2-yn-1-yl 2-cyclohexyl-2-hydroxy-2-phenylacetate monohydrochloride monohydrate. 2nd communication: tissue levels and enzyme activity in rats after repeated administration, and placental and milk transfer after single administration.

Nakamura A, Hirota T, Sugihara K, Watanabe S, Tougou K, Morino A, Ezumi Y, Takaichi M. Nakamura A, et al. Arzneimittelforschung. 1997 Feb;47(2):160-8. Arzneimittelforschung. 1997. PMID: 9079235

6

N-oxidation of irsogladine by the CYP2C subfamily in the rat, dog, monkey and man.

Nakamura A, Hirota T, Morino A, Shimada T, Uematsu T. Nakamura A, et al. Xenobiotica. 1997 Oct;27(10):995-1003. doi: 10.1080/004982597239976. Xenobiotica. 1997. PMID: 9364737

7

Paraoxonase has a major role in the hydrolysis of prulifloxacin (NM441), a prodrug of a new antibacterial agent.

Tougou K, Nakamura A, Watanabe S, Okuyama Y, Morino A. Tougou K, et al. Among authors: nakamura a. Drug Metab Dispos. 1998 Apr;26(4):355-9. Drug Metab Dispos. 1998. PMID: 9531524

8

Effects of urinary metabolites of etodolac on diagnostic tests of bilirubin in urine.

Sho Y, Ishiodori T, Oketani M, Kubozono O, Nakamura A, Takeuchi A, Morino A, Arima T. Sho Y, et al. Among authors: nakamura a. Arzneimittelforschung. 1999 Jul;49(7):572-6. doi: 10.1055/s-0031-1300464. Arzneimittelforschung. 1999. PMID: 10442203 Clinical Trial.

9

Effects of etodolac on P450 isoform-specific activities in human hepatic microsomes.

Nakamura A, Tougou K, Kitazumi H, Yamada T, Honjou K, Zinno A, Nonaka K, Mukai H. Nakamura A, et al. Arzneimittelforschung. 2005;55(12):744-8. doi: 10.1055/s-0031-1296924. Arzneimittelforschung. 2005. PMID: 16430028

10

Species differences in the disposition and metabolism of camazepam.

Morino A, Nakamura A, Nakanishi K, Tatewaki N, Sugiyama M. Morino A, et al. Among authors: nakamura a. Xenobiotica. 1985 Dec;15(12):1033-43. doi: 10.3109/00498258509049098. Xenobiotica. 1985. PMID: 2868575

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