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Effect of structural modification of enol-carboxamide-type nonsteroidal antiinflammatory drugs on COX-2/COX-1 selectivity.
J Med Chem. 1997 Mar 14;40(6):980-9. doi: 10.1021/jm9607010.
J Med Chem. 1997.
PMID: 9083488
Discovery of 2-phenylamino-imidazo[4,5-h]isoquinolin-9-ones: a new class of inhibitors of lck kinase.
Snow RJ, Cardozo MG, Morwick TM, Busacca CA, Dong Y, Eckner RJ, Jacober S, Jakes S, Kapadia S, Lukas S, Panzenbeck M, Peet GW, Peterson JD, Prokopowicz AS 3rd, Sellati R, Tolbert RM, Tschantz MA, Moss N.
Snow RJ, et al. Among authors: tschantz ma.
J Med Chem. 2002 Aug 1;45(16):3394-405. doi: 10.1021/jm020113o.
J Med Chem. 2002.
PMID: 12139450
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Optimization of 2-phenylaminoimidazo[4,5-h]isoquinolin-9-ones: orally active inhibitors of lck kinase.
Goldberg DR, Butz T, Cardozo MG, Eckner RJ, Hammach A, Huang J, Jakes S, Kapadia S, Kashem M, Lukas S, Morwick TM, Panzenbeck M, Patel U, Pav S, Peet GW, Peterson JD, Prokopowicz AS 3rd, Snow RJ, Sellati R, Takahashi H, Tan J, Tschantz MA, Wang XJ, Wang Y, Wolak J, Xiong P, Moss N.
Goldberg DR, et al. Among authors: tschantz ma.
J Med Chem. 2003 Apr 10;46(8):1337-49. doi: 10.1021/jm020446l.
J Med Chem. 2003.
PMID: 12672234
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